Results 141 to 150 of about 47,794 (286)

IL‐15 Plus Thymosin α1 Reduces Senescent Hepatic CD8+ T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression

Journal of Gastroenterology and Hepatology, EarlyView.
Combined IL‐15 and thymosin α1 therapy reverses CD8+ T cell senescence in hepatocellular carcinoma via a “supply and boost” strategy. Tα1 restores thymic naïve T cell output, while IL‐15 enhances peripheral effector function. Mechanistically, this combination suppresses overactivated PI3K/AKT signaling, restoring antitumor immunity and prolonging ...
Fengtian Wu, Zixuan Guo, Jun Guan, Jia Xu, Yao Chen, Zhi Chen   +5 more
wiley   +1 more source

Structure of human C8 suggests how complement forms circular membrane pores [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2011
L. Lebioda, L. L. Lovelace, C. L. Cooper, J. M. Sodetz   +3 more
openaire   +1 more source

Updating the forelimb anatomy of the domestic cat (Felis catus, Felidae) based on evolutionary inferences of its muscles and nerves I: Shoulder and brachium

Journal of Anatomy, EarlyView.
In this study, we provide a detailed description of the shoulder and brachium muscles and the brachial plexus of the domestic cat (Felis catus). We identified muscular variants (articularis humeri, coracobrachialis longus, biceps brachii caput breve), clarified the independence of the anconeus medialis muscle from the triceps brachii muscle, and ...
Juan Fernando Vélez García, Ismael Vélez Cabrera, Maria Angelica Miglino   +2 more
wiley   +1 more source

Timing and Trajectories: Shifts in Migration and Family Formation Trajectories in Nepal

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study identifies distinct pathways of migration, marriage, and childbearing among young men in Nepal, a context characterized by short‐term circular migration as well as rapid social and demographic change, and examines how these transitions vary by key sociodemographic characteristics.
Emma Labovitz, Ka U. Ng
wiley   +1 more source

How Well Do We Know How Others See Us? A Systematic Review of Meta‐Accuracy Across Relational Contexts, Research Foci, Attribute Domains, and Measurement Approaches

Journal of Personality, EarlyView.
ABSTRACT Introduction Meta‐accuracy, the degree to which individuals accurately infer how others perceive them, is fundamental to social interactions. Yet the field draws on diverse methods across disciplines, and variation in conceptualizations and approaches has not been systematically captured.
Craig Harper, Melissa Cameron, Lucy Albertella, Odkhishig Ganbold, Campbell Ince, Lars Kooijman, Maria Suetin, Benjamin Kozoolin, Murat Yücel, Kristian Rotaru   +9 more
wiley   +1 more source

Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis. [PDF]

Sci Rep
Langhoff L, Kapfer P, Röttgerding F, Margos G, Hepner S, Fingerle V, Sato K, Kawabata H, Lin YP, Brangulis K, Rollins RE, Kraiczy P.   +11 more
europepmc   +1 more source

The Core‐Periphery Model Under Additively Separable Preferences

Journal of Regional Science, Volume 65, Issue 2, Page 378-402, March 2025.
ABSTRACT This paper reexamines Krugman's core‐periphery model by substituting his constant elasticity of substitution (CES) utility with a general additively separable utility that comprehensively captures the pro‐competitive effect while preserving the income effect.
Congcong Wang, Dao‐Zhi Zeng, Xiwei Zhu
wiley   +1 more source

Testing Distributional Granger Causality With Entropic Optimal Transport

Journal of Time Series Analysis, EarlyView.
ABSTRACT We develop a novel nonparametric test for Granger causality in distribution based on entropic optimal transport. Unlike classical mean‐based approaches, the proposed method directly compares the full conditional distributions of a response variable with and without the history of a candidate predictor.
Tao Wang
wiley   +1 more source

Complement C9 deficiency as a novel risk factor for invasive Candida esophagitis in children: a single case in-depth analysis. [PDF]

BMC Pediatr
Zheng G, Zhang J, Peng K, Tang L, Tan Z, Gu W, Wang Y.   +6 more
europepmc   +1 more source

Plasmatic Profiling of Individuals With Combinations of Type 2 Diabetes Mellitus, Dyslipidemia and Periodontitis: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira, Sâmia Cruz Tfaile Corbi, Alliny de Souza Bastos, Silvana Regina Perez Orrico, Cristiane Ribeiro Salmon, Yizhi Xiao, Walter Luiz Siqueira, Raquel Mantuaneli Scarel‐Caminaga   +7 more
wiley   +1 more source