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Early Serum Free Light Chain Response in Newly Diagnosed Multiple Myeloma: Documented Earlier Than MRD and Complementary in Prognosis. [PDF]
Pan Y +5 more
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Molecular reporters for mammalian sugars <i>via</i> hydrogen bonding auxiliaries. [PDF]
Wang Y +6 more
europepmc +1 more source
Post-ischemia and reperfusion kidney injury is mitigated in a novel complement 5 knockout rat. [PDF]
McGraw M +7 more
europepmc +1 more source
Proteomics Analysis Reveals Serum Biomarkers Reflecting Joint Pain and Physical Limitations in Knee Osteoarthritis Before and After Joint Replacement Surgery. [PDF]
Mustonen AM +11 more
europepmc +1 more source
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Biochemistry, 2000
Human C8 is one of five complement components (C5b, C6, C7, C8, and C9) that interact to form the cytolytic membrane attack complex, or MAC. It is an oligomeric protein composed of three subunits (C8alpha, C8beta, C8gamma) that are products of different genes.
M E, Plumb, J M, Sodetz
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Human C8 is one of five complement components (C5b, C6, C7, C8, and C9) that interact to form the cytolytic membrane attack complex, or MAC. It is an oligomeric protein composed of three subunits (C8alpha, C8beta, C8gamma) that are products of different genes.
M E, Plumb, J M, Sodetz
openaire +5 more sources
Genetic polymorphism of complement component C8
Human Genetics, 1985Extensive genetic polymorphism of complement component C8 was demonstrated by isoelectric focusing of serum or plasma samples followed by immunoblotting procedures. Using these methods, we could detect both alpha-gamma (C81) and beta (C82) chain polymorphisms in the same gel.
S, Rogde +5 more
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A familial dysfunction of the eighth component of complement (C8)
Clinical Immunology and Immunopathology, 1980Abstract A 6-year-old boy, who presented with hepatosplenomegaly, moderately elevated erythrocyte sedimentation rate, hypergammaglobulinemia, and eosinophilia, was found to have very low or undetectable serum C8 hemolytic activity. This activity was restored to normal by the addition of purified C8.
F, Tedesco +3 more
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The Terminal Complement Complex in Sera Deficient in the Eighth Component of Complement (C8)
Scandinavian Journal of Immunology, 1986The terminal complement complex (TCC) was quantified in sera from patients with a genetic deficiency of C8α‐γ or C8β The individual sera contained only trace amounts of TCC compared with a normal serum pool. The content of TCC increased after mixing the two sera, which was consistent with reconstitution of C8 activity.
T E, Mollnes +3 more
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