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Experimental Inhibition of Complement
1969Four methods are available to elucidate the biological significance of the serum-complement system: 1. The demonstration of complement components at the site of the immunological event. 2. Investigation with animals possessing a genetic C defect. 3. Experiments with anticomplement substances and 4.
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Inhibition of Complement Fixation by Rabbit Serum
The Journal of Immunology, 1960Summary The fixation of guinea pig complement by aggregates of rabbit antibody against ovalbumin and ovalbumin is impeded by normal rabbit serum. The inhibitory effect of rabbit serum is a function of the γ-globulin fraction. Prolonged storage in the cold, or heating at 56–65°C for 1 hr or less have no significant effect on this activity
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Compstatins: The Dawn of Clinical C3-Targeted Complement Inhibition
Trends in Pharmacological Sciences, 2022Daniel Ricklin +2 more
exaly
INHIBITION OF COMPLEMENT‐DERIVED ENZYMES*
Annals of the New York Academy of Sciences, 1975D T, Fearon, K F, Austen
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Inhibition of complement activation by IgG4 antibodies.
Clinical and experimental immunology, 1986Prolonged exposure to antigens may result in high IgG4 antibody titres as was shown in a previous paper (Aalberse et al., 1983b). In novice bee keepers, a shift in the IgG1/IgG4 ratio of the response against phospholipase-A (PLA; a major component of bee venom) occurred.
van der Zee, J. S. +2 more
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