Results 241 to 250 of about 343,841 (303)

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Collectin-11 regulates osteoclastogenesis and bone maintenance via a complement-dependent mechanism. [PDF]

Proc Natl Acad Sci U S A
Howard MC, Farrar CA, Nauser CL, Jeon Y, Polycarpou A, Smolarek D, Greenlaw R, Foster M, Garred P, Vizitiu DA, Mukhopadhyay S, Sacks SH.   +11 more
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Targeting the lectin pathway in TA-TMA. [PDF]

Blood Adv
Jodele S.
europepmc   +1 more source

Xenotransplantation: principles and practice [PDF]

, 1996
Fung, JJ, Starzl, TE, Todo, S, Valdivia, L   +3 more
core  

Self‐Sintering Ionogel Binder for Flexible, Recyclable, and Healable Printed Giant Magnetoresistive Sensors

Advanced Functional Materials, EarlyView.
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo, Xiaotao Wang, Guannan Mu, Proloy Taran Das, Igor Veremchuk, Conrad Schubert, Aaron D. Cross, Yevhen Zabila, Xuan Peng, Larysa Baraban, Denys Makarov   +10 more
wiley   +1 more source

Population PK-PD Modeling of Danicopan Add-On Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria Treated With Ravulizumab or Eculizumab. [PDF]

CPT Pharmacometrics Syst Pharmacol
Chen J, Yang F, Li H, Pradhan R, Ortiz S.   +4 more
europepmc   +1 more source

Plasma Proteomic Signatures of Pediatric Sepsis Reveal Persistent Inflammation and Phase-Specific Biomarkers. [PDF]

FASEB Bioadv
Alhamdan F, Sin YC, Malm E, Van Pelt H, Kim S, Higgins L, Chen Y, Yuki K.   +7 more
europepmc   +1 more source

Present Advances and Emerging Challenges in Kidney Xenotransplantation. [PDF]

J Clin Med
Yamanaka K, Kakuta Y, Miyagawa S, Inoue K, Matsumura S, Fukae S, Kawamura M, Nakazawa S, Kobayashi K, Kageyama S, Nonomura N.   +10 more
europepmc   +1 more source

Complement activation in immunological neurological disorders: mechanisms and therapeutic strategies. [PDF]

Front Neurol
Chen JY, Sanghani N, Palmer K, Li Y, Lin F, Abbatemarco JR.   +5 more
europepmc   +1 more source