Results 51 to 60 of about 425,149 (322)
Metalated Porous-Organic-Polymer Renders Mustard-Gas Simulant Harmless: Core Planarity Matters [PDF]
arXiv, 2022 The presence of open active metal sites in Metal-Organic Frameworks (MOFs) exhibit higher catalytic activity. However, rational accomplishment of MOFs in heterogeneous catalysis is limited due to coordination bonds. Recently balanced characteristic feature with combination of both the covalent bonds (structural stability) and open metal sites (single ...
arxiv
Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice. [PDF]
PLoS ONE, 2016 Streptococcus pneumoniae is a common cause of sepsis. Effective complement activation is an important component of host defence against invading pathogens, whilst excessive complement activation has been associated with endothelial dysfunction and organ ...
Erika van der Maten +7 more
doaj +1 more source
Immune Adherence by the Alternate Complement Pathway
Experimental Biology and Medicine, 1972 SummaryThe ability of the alternate complement pathway to generate the immune adherence reaction was studied in C4D guinea pig sera. It was found that IA via the alternate pathway could be generated by endotoxins and immune complexes, but that this phenomenon could not be produced by optimally sensitized intact mammalian cell membranes.
Joseph E. May +2 more
openaire +3 more sources
, 2018 Understanding the role of alternative complement pathway dysregulation in membranoproliferative glomerulonephritis (MPGN) has led to a new classification into two subgroups: immune complex-mediated MPGN and complement-mediated MPGN.
Kojc, Nika
core +2 more sources
Current Issues in Molecular Biology, 2023 Heme (Fe2+-protoporphyrin IX) is a pigment of life, and as a prosthetic group in several hemoproteins, it contributes to diverse critical cellular processes. While its intracellular levels are tightly regulated by networks of heme-binding proteins (HeBPs)
Stefanos A. Tsiftsoglou
doaj +1 more source
Alternative Pathway Dysregulation and the Conundrum of Complement Activation by IgG4 Immune Complexes in Membranous Nephropathy [PDF]
, 2016 Membranous nephropathy (MN), a major cause of nephrotic syndrome, is a non-inflammatory immune kidney disease mediated by IgG antibodies that form glomerular subepithelial immune complexes.
Dorin-Bogdan Borza
core +2 more sources
A meridian lemma for fully alternating links in thickened surfaces [PDF]
arXiv, 2022 Menasco showed that a closed surface in the complement of a non-split prime alternating link in $S^3$ contains a circle isotopic in the link complement to a meridian of the links. This result is known as the meridian lemma for alternating links. We give a meridian lemma for the class of fully alternating links in the thickened orientable surfaces of ...
arxiv
A machine learning approach to investigate regulatory control circuits in bacterial metabolic pathways [PDF]
, 2020 In this work, a machine learning approach for identifying the multi-omics metabolic regulatory control circuits inside the pathways is described. Therefore, the identification of bacterial metabolic pathways that are more regulated than others in term of their multi-omics follows from the analysis of these circuits .
arxiv +1 more source
Electronic transport in single-helical protein molecules: Effects of multiple charge conduction pathways and helical symmetry [PDF]
Physics Letters A 380, 2395 (2016), 2016 We propose a tight-binding model to investigate electronic transport properties of single helical protein molecules incorporating both the helical symmetry and the possibility of multiple charge transfer pathways. Our study reveals that due to existence of both the multiple charge transfer pathways and helical symmetry, the transport properties are ...
arxiv +1 more source
Frontiers in Immunology, 2023 Properdin acts as an essential positive regulator of the alternative pathway of complement by stabilizing enzymatic convertases. Identical properdin monomers form head-to-tail associations of oligomers in a reported 20:54:26 ratio (most often described ...
Sara R. Moore +5 more
doaj +1 more source