Results 1 to 10 of about 305,892 (307)

Hemopexin Modulates Expression of Complement Regulatory Proteins in Rat Glomeruli [PDF]

Current Issues in Molecular Biology, 2021
In systemic hemolysis and in hematuric forms of kidney injury, the major heme scavenging protein, hemopexin (HPX), becomes depleted, and the glomerular microvasculature (glomeruli) is exposed to high concentrations of unbound heme, which, in addition to ...
Maria G. Detsika, Elias A. Lianos
doaj   +8 more sources

Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection [PDF]

Malaria Journal, 2019
Background Anaemia is a major consequence of malaria, caused by the removal of both infected and uninfected red blood cells (RBCs) from the circulation. Complement activation and reduced expression of complement regulatory proteins (CRPs) on RBCs are an ...
Damian A. Oyong, Jessica R. Loughland, Arya SheelaNair, Dean Andrew, Fabian D. L. Rivera, Kim A. Piera, Timothy William, Matthew J. Grigg, Bridget E. Barber, Ashraful Haque, Christian R. Engwerda, James S. McCarthy, Nicholas M. Anstey, Michelle J. Boyle   +13 more
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The effect of splenectomy on complement regulatory proteins in erythrocytes in β-thalassemia major [PDF]

Archives of Medical Science, 2018
Introduction Hemolysis due to ineffective erythropoiesis is a serious problem β-thalassemia major (β-TM) patients. The role of complement system in the etiopathogenesis of hemolysis observed in β-TM were released.
Ayşegül Uğur Kurtoğllu, Belkıs Koçtekin, Erdal Kurtoğlu, Mustafa Yildiz   +3 more
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Complement proteins and complement regulatory proteins are associated with age-related macular degeneration stage and treatment response [PDF]

Journal of Neuroinflammation
Background Dysregulation of the complement system is involved in development of age-related macular degeneration (AMD). The complement cascade is regulated by membrane bound complement regulatory proteins (Cregs) on mononuclear leukocytes among others ...
Alexander Kai Thomsen, Maria Abildgaard Steffensen, Jenni Martinez Villarruel Hinnerskov, Amalie Thomsen Nielsen, Henrik Vorum, Bent Honoré, Mogens Holst Nissen, Torben Lykke Sørensen   +7 more
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SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins [PDF]

Emerging Microbes and Infections
Complement hyperactivation and thrombotic microangiopathy are closely associated with severe COVID-19. Endothelial dysfunction is a key mechanism underlying thrombotic microangiopathy.
Jian Wu, Sanpeng Xu, Zhiqing Li, Boyi Cong, Zongheng Yang, Zhichao Yang, Wanfeng Gao, Shuo Liu, Zhou Yu, Sheng Xu, Nan Li, Jin Hou, Guoping Wang, Xuetao Cao, Shuxun Liu   +14 more
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Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion [PDF]

Frontiers in Microbiology, 2016
The human complement system plays an important role in the defense against invading pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly activate the complement system resulting in the formation of chemoattractants and ...
Elise Sofie Hovingh, Elise Sofie Hovingh, Bryan van den Broek, Ilse Jongerius, Ilse Jongerius   +4 more
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Expression levels of complement regulatory proteins (CD35, CD55 and CD59) on peripheral blood cells of patients with chronic kidney disease [PDF]

International Journal of General Medicine, 2019
Dalia Mahmoud Eldewi,1 Alshaymaa M Alhabibi,1 Hanaa Mohammed Eid El Sayed,2 Sammar Ahmed Kasim Mahmoud,2 Sanaa Mohammed El Sadek,3 Rasha Mahmoud Gouda,3 Mohammed Abd El Malik Hassan,4 Amal H Ibrahim,2 Naglaa F Abd El Haliem5 1Clinical Pathology ...
Eldewi DM, Alhabibi AM, El Sayed HME, Mahmoud SAK, El Sadek SM, Gouda RM, Hassan MAEM, Ibrahim AH, Abd El Haliem NF   +8 more
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Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat [PDF]

Antioxidants, 2022
Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression of complement ...
Maria G. Detsika, Eirini Theochari, Kostas Palamaris, Harikleia Gakiopoulou, Elias A. Lianos   +4 more
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Complement regulatory proteins: Candidate biomarkers in differentiating tuberculosis pleural effusion [PDF]

Frontiers in Immunology, 2023
Background and aimsComplement activation is essential for tuberculosis pleural effusion. However, little is known about the value of complement regulatory protein (CD46, CD55, and CD59) in the differential diagnosis of tuberculosis.Materials and ...
Huan Tang, Huan Tang, Xinyue Hu, Xinyue Hu, Li Li, Shuanglinzi Deng, Shuanglinzi Deng, Yuanyuan Jiang, Yuanyuan Jiang, Lisha Luo, Lisha Luo, Runjin Cai, Runjin Cai, Yifei Yang, Yifei Yang, Chendong Wu, Chendong Wu, Xiaoxiao Gong, Xiaoxiao Gong, Juntao Feng, Juntao Feng   +20 more
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Entamoeba histolytica Develops Resistance to Complement Deposition and Lysis after Acquisition of Human Complement-Regulatory Proteins through Trogocytosis [PDF]

mBio, 2022
Entamoeba histolytica is the cause of amoebiasis. The trophozoite (amoeba) form of this parasite is capable of invading the intestine and can disseminate through the bloodstream to other organs.
Hannah W. Miller, Tammie S. Y. Tam, Katherine S. Ralston   +2 more
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