Role of complement and complement regulatory proteins in the complications of diabetes.
Endocr Rev, 2015 It is well established that the organ damage that complicates human diabetes is caused by prolonged hyperglycemia, but the cellular and molecular mechanisms by which high levels of glucose cause tissue damage in humans are still not fully understood.
Ghosh P +4 more
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Combating Complement's Deleterious Effects on Nanomedicine by Conjugating Complement Regulatory Proteins to Nanoparticles. [PDF]
Adv Mater, 2022 AbstractComplement opsonization is among the biggest challenges facing nanomedicine. Nearly instantly after injection into blood, nanoparticles are opsonized by the complement protein C3, leading to clearance by phagocytes, fouling of targeting moieties, and release of anaphylatoxins. While surface polymers such as poly(ethylene glycol) (PEG) partially
Wang Z +14 more
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Expression levels of complement regulatory proteins (CD35, CD55 and CD59) on peripheral blood cells of patients with chronic kidney disease [PDF]
International Journal of General Medicine, 2019 Dalia Mahmoud Eldewi,1 Alshaymaa M Alhabibi,1 Hanaa Mohammed Eid El Sayed,2 Sammar Ahmed Kasim Mahmoud,2 Sanaa Mohammed El Sadek,3 Rasha Mahmoud Gouda,3 Mohammed Abd El Malik Hassan,4 Amal H Ibrahim,2 Naglaa F Abd El Haliem5 1Clinical Pathology ...
Eldewi DM +8 more
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Function of complement regulatory proteins in immunity of reproduction: a review [PDF]
Czech Journal of Animal Science, 2005 Humoral immunity has an important role during the maturation and development of the functional properties of spermatozoa. Spermatozoa may be exposed to antisperm antibodies in semen and in cervical, ovarian follicular and fallopian fluid.
J. Valentovičová +2 more
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Review: Complement and its regulatory proteins in kidney diseases [PDF]
Nephrology, 2010 ABSTRACTComplement is a part of the body's innate immune system that helps defend the host from microbial infection. It is tightly controlled by a number of cell surface and fluid‐phase proteins so that under normal circumstances injury to autologous tissues is avoided.
Allison M. Lesher, Wen‐Chao Song
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Evolution of red blood cell membrane complement regulatory proteins and rheology in septic patients: An exploratory study. [PDF]
Front Med (Lausanne), 2022 Vanderelst J +5 more
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Chandipura virus evades human complement by recruiting host complement regulatory proteins
International Journal of Infectious Diseases, 2020 U. Kunnakkadan, J. Bernet Johnson
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Upregulation of complement proteins in lung cancer cells mediates tumor progression
Frontiers in Oncology, 2023 IntroductionIn vivo, cancer cells respond to signals from the tumor microenvironment resulting in changes in expression of proteins that promote tumor progression and suppress anti-tumor immunity.
Emily K. Kleczko +16 more
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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Laboratory tests for disorders of complement and complement regulatory proteins [PDF]
American Journal of Hematology, 2015 The complement pathway is a cascade of proteases that is involved in immune surveillance and innate immunity, as well as adaptive immunity. Dysfunction of the complement cascade may be mediated by aberrations in the pathways of activation, complement regulatory proteins, or complement deficiencies, and has been linked to a number of hematologic ...
Mandakolathur R. Murali, Angela R. Shih
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