Results 171 to 180 of about 24,757,633 (403)
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
INTERACTIONS OF THE COMPLEMENT SYSTEM WITH ENDOTOXIC LIPOPOLYSACCHARIDE [PDF]
Ralph Snyderman+2 more
openalex +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Studies on the Role of Complement in the Immune Clearance of Escherichia Coli and Rat Erythrocytes by the Reticuloendothelial System in Mice [PDF]
Hans L. Spiegelberg+2 more
openalex +1 more source
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Editorial: Complement in nervous system disease
Iliana Michailidou+4 more
doaj +1 more source
Molecular and Structural Damage toEscherichia coliProduced by Antibody, Complement, and Lysozyme Systems [PDF]
Lawrence Wilson, John K. Spitznagel
openalex +1 more source
Cohomology of Complements of Toric Arrangements Associated to Root Systems [PDF]
We compute the cohomology of the complement of toric arrangements associated to root systems as representations of the corresponding Weyl groups. Specifically, we develop an algorithm for computing the cohomology of the complement of toric arrangements associated to general root systems and we carry out this computation for the exceptional root systems
arxiv
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
Kinetic Assessment of Alternative Complement Pathway Activity in A Hemolytic System [PDF]
Rutherford B. Polhill+2 more
openalex +3 more sources