Results 181 to 190 of about 24,198,541 (380)

Interactions of C-reactive protein with the complement system. III. Complement-dependent passive hemolysis initiated by CRP. [PDF]

, 1975
Alexander P. Osmand, Richard F. Mortensen, J N Siegel, H Gewurz   +3 more
openalex   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Correlation of Circulating Complement Levels with Clinical Characteristics of Patients with Diabetic Retinopathy

International Journal of General Medicine
Guangjiang Wang, Yuan Guo Department of Ophthalmology, The Fourth Hospital of Baotou, Baotou City, Inner Mongolia Autonomous Region, 014030, People’s Republic of ChinaCorrespondence: Yuan Guo, Department of Ophthalmology, The Fourth Hospital of Baotou ...
Wang G, Guo Y
doaj  

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Editorial: Current challenges in complement diagnostics

Frontiers in Immunology, 2023
Per H. Nilsson, Per H. Nilsson, Lillemor Skattum, Lillemor Skattum, Erik J. M. Toonen   +4 more
doaj   +1 more source

Genetic diversity and population structure of the Taigan dog breed

FEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova, Anastassiya Perfilyeva, Мamura Begmanova, Assel Zhaxylykova, Arailym Yerzhan, Kanagat Yergali, Almazbek Akunov, Marat Munarbek uulu, Anna Khamchukova, Almira Amirgaliyeva, Yelena Kuzovleva   +10 more
wiley   +1 more source

Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

Cell Reports, 2018
Summary: Complement-mediated cytotoxicity may act as a selective pressure for tumor overexpression of complement regulators. We hypothesize that the same selective pressure could lead to complement alterations at the genetic level.
Monica M. Olcina, Nikolas G. Balanis, Ryan K. Kim, B. Arman Aksoy, Julia Kodysh, Michael J. Thompson, Jeff Hammerbacher, Thomas G. Graeber, Amato J. Giaccia   +8 more
doaj  

Specific enhancement of the cytotoxic titre with regard to complement source and cytotoxicity test systems [PDF]

, 1972
H.-D. Adolphs
openalex   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

FEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez, Paulina Torres, Gabriela Carrasquel‐Martínez, María G. Figueroa‐Méndez, Diana Flores, Lina Villar, Israel Maldonado, Marcela B. Trevino, Claudia Treviño   +8 more
wiley   +1 more source