Results 181 to 190 of about 1,195,438 (288)

CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system. [PDF]

Gene Ther
Salman A, Song WK, Storm T, McClements ME, MacLaren RE.   +4 more
europepmc   +2 more sources

An intracellular complement system drives metabolic and proinflammatory reprogramming of vascular fibroblasts in pulmonary hypertension. [PDF]

JCI Insight
Prasad RR, Kumar S, Zhang H, Li M, Hu CJ, Riddle S, McKeon BA, Frid MG, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Tuder RM, Stenmark KR.   +12 more
europepmc   +1 more source

Subversion of the Complement System by Pseudomonas aeruginosa. [PDF]

J Bacteriol, 2023
Hastings CJ, Syed SS, Marques CNH.
europepmc   +1 more source

Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19. [PDF]

, 1991
A K Matsumoto, J A Kopicky-Burd, R H Carter, David A. Tuveson, Thomas F. Tedder, Douglas T. Fearon   +5 more
openalex   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

The Role of the Complement System in the Pathogenesis of Infectious Forms of Hemolytic Uremic Syndrome. [PDF]

Biomolecules, 2023
Avdonin PP, Blinova MS, Generalova GA, Emirova KM, Avdonin PV.   +4 more
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

A bipartite bacterial virulence factor targets the complement system and neutrophil activation. [PDF]

EMBO J
Kurniyati K, Clark ND, Wang H, Deng Y, Sze CW, Visser MB, Malkowski MG, Li C.   +7 more
europepmc   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

The Interactions of the Complement System with Human Cytomegalovirus. [PDF]

Viruses
Lujan E, Zhang I, Garon AC, Liu F.
europepmc   +1 more source