Results 11 to 20 of about 2,103,871 (307)
The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
doaj +1 more source
Research Progress on the Fish Complement C3 Gene [PDF]
, 2023 Complement (C) is a serum protein with immunity-related functions and enzymatic activities. It can induce inflammatory responses and antibody formation following activation by substances such as pathogens.
Chen, Fuyan +11 more
core +2 more sources
International Journal of Molecular Sciences, 2023 The crosstalk among the complement system, immune cells, and mediators of inflammation provides an efficient mechanism to protect the organism against infections and support the repair of damaged tissues. Alterations in this complex machinery play a role
F. Lasorsa +10 more
semanticscholar +1 more source
Virus-Encoded Complement Regulators: Current Status
Viruses, 2021 Viruses require a host for replication and survival and hence are subjected to host immunological pressures. The complement system, a crucial first response of the host immune system, is effective in targeting viruses and virus-infected cells, and ...
Anwesha Sinha +4 more
doaj +1 more source
Complement System in Alzheimer’s Disease
International Journal of Molecular Sciences, 2021 Alzheimer’s disease is a type of dementia characterized by problems with short-term memory, cognition, and difficulties with activities of daily living. It is a progressive, neurodegenerative disorder.
A. Shah, U. Kishore, A. Shastri
semanticscholar +1 more source
Frontiers in Aging Neuroscience, 2022 BackgroundThe immune response and the complement system are associated with cognitive impairment and diabetes mellitus, respectively. Activation of the complement system in these diseases occurs mainly through either the classical pathway or the ...
Zhenxing Li +7 more
doaj +1 more source
Targeting the complement system in neuromyelitis optica spectrum disorder
Expert Opinion on Biological Therapy, 2021 Introduction Neuromyelitis optica spectrum disorder (NMOSD) is characterized by central nervous system inflammation and demyelination. In AQP4-IgG seropositive NMOSD, circulating immunoglobulin G (IgG) autoantibodies against astrocyte water channel ...
Nithi Asavapanumas +2 more
semanticscholar +1 more source
Cells, 2021 The complement system, an effector arm of the innate immune system that plays a critical role in tissue inflammation, the elimination of pathogens and the clearance of dead cells and cell debris, has emerged as a regulator of many processes in the ...
M. Pekna, M. Pekny
semanticscholar +1 more source
Aberrant Complement System Activation in Neurological Disorders
International Journal of Molecular Sciences, 2021 The complement system is an assembly of proteins that collectively participate in the functions of the healthy and diseased brain. The complement system plays an important role in the maintenance of uninjured (healthy) brain homeostasis, contributing to ...
Karolina Ziabska +4 more
semanticscholar +1 more source
Components of the Complement Cascade Differ in Polycystic Ovary Syndrome [PDF]
, 2022 Complement pathway proteins are reported to be increased in polycystic ovary syndrome (PCOS) and may be affected by obesity and insulin resistance. To investigate this, a proteomic analysis of the complement system was undertaken, including inhibitory ...
Atkin, Stephen L. +3 more
core +1 more source