Results 41 to 50 of about 2,132,131 (391)
Cells, 2021 The complement system, an effector arm of the innate immune system that plays a critical role in tissue inflammation, the elimination of pathogens and the clearance of dead cells and cell debris, has emerged as a regulator of many processes in the ...
M. Pekna, M. Pekny
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Frontiers in Cellular Neuroscience, 2021 As part of the innate immune system, complement plays a critical role in the elimination of pathogens and mobilization of cellular immune responses. In the central nervous system (CNS), many complement proteins are locally produced and regulate nervous ...
Noriko Shinjyo +4 more
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The Role of Complement System and the Immune Response to Tuberculosis Infection
Medicina, 2021 The complement system orchestrates a multi-faceted immune response to the invading pathogen, Mycobacterium tuberculosis. Macrophages engulf the mycobacterial bacilli through bacterial cell surface proteins or secrete proteins, which activate the ...
H. Jagatia, Anthony G. Tsolaki
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Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance [PDF]
Iranian Journal of Immunology, 2023 Two central questions in COVID-19 treatment which should be considered are: “How does the imbalance of the complement system affect the therapeutic approaches?” and “Do we consider complement inhibitors in therapeutic protocols?”.
Mehdi Torabizadeh +5 more
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Profiling Complement System Components in Primary CNS Vasculitis
Cells, 2021 Complement activation has been implicated in the pathogenesis of many vasculitic syndromes such as anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
Milani Deb-Chatterji +6 more
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Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host
Frontiers in Microbiology, 2019 Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
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Research Progress on the Fish Complement C3 Gene [PDF]
, 2023 Complement (C) is a serum protein with immunity-related functions and enzymatic activities. It can induce inflammatory responses and antibody formation following activation by substances such as pathogens.
Chen, Fuyan +11 more
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Local Activation of the Alternative Pathway of Complement System in Mycotic Keratitis Patient Tear
Frontiers in Cellular and Infection Microbiology, 2020 Aspergillus flavus and Fusarium solani are the predominant causative agents of mycotic keratitis in the tropical part of the world. Tear proteins play a major role in the innate immune response against these fungal infections as has been shown by the ...
Mohammed Razeeth Shait Mohammed +6 more
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Mast cells and complement system: Ancient interactions between components of innate immunity
Allergy. European Journal of Allergy and Clinical Immunology, 2020 The emergence and evolution of the complement system and mast cells (MCs) can be traced back to sea urchins and the ascidian Styela plicata, respectively. Acting as a cascade of enzymatic reactions, complement is activated through the classical (CP), the
Daniel Elieh-Ali-Komi +3 more
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Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins
Frontiers in Immunology, 2021 Early and persistent activation of complement is considered to play a key role in the pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory environment that might be critical for the induction and maintenance of a severe ...
Youssif M. Ali +8 more
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