Results 101 to 110 of about 9,405 (288)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Complementizer drop and clitic climbing in Torlakian: Evidence from the Timok variety

open access: yesBalcania et Slavia
The paper is based on a corpus study of the complementizer da drop (Comp_drop) and clitic climbing (CC) in the Timok variety of Serbian. Data are taken from the Spoken Torlak dialect corpus 1.0 (Vuković 2020) and comprise over 900 examples of ...
Miric, Mirjana
doaj   +1 more source

Structural and sociolectal limits of variability of que in Mexican Spanish noun clefts

open access: yesIsogloss
This paper investigates the structural and sociolectal limits of the use of non-standard “plain” que instead of the standard relativizer DET+que in Mexican Spanish noun clefts.
Patrick Auhagen, Jan Fliessbach
doaj   +1 more source

On an alternative to long A´-movement in German and Dutch [PDF]

open access: yes, 2008
This paper provides an analysis of an alternative strategy to A´-movement in both German and Dutch where the extracted constituent is preceded by a preposition and a coreferential pronoun appears in the extraction site. The construction has properties of
Salzmann, Martin
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Word order in the Old Italian DP [PDF]

open access: yes, 2015
In this article I examine the impact of a cartographic approach on research about diachronic change and investigate the internal structure of the DP in Old Italian (OI).
Poletto, Cecilia
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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