Results 81 to 90 of about 616,916 (268)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The complete chloroplast genome sequence of Spathodea campanulata

Mitochondrial DNA. Part B. Resources, 2019
The first complete chloroplast genome (cpDNA) sequence of Spathodea campanulata was determined from Illumina HiSeq pair-end sequencing data in this study.
Yi Wang, Xiaolong Yuan, Yunqing Li, Jinfeng Zhang   +3 more
doaj   +1 more source

Complete genome sequence of Rhizobium leguminosarum bv trifolii strain WSM2304, an effective microsymbiont of the South American clover Trifolium polymorphum.

, 2010
Rhizobium leguminosarum bv trifolii is the effective nitrogen fixing microsymbiont of a diverse range of annual and perennial Trifolium (clover) species.
Alex Copeland, John Howieson, Mavromatis, K, Nolan, M, Victor Markowitz, Nandasena, K.G., Konstantinos Mavromatis, Lambert Bräu, Natalia Ivanova, Ardley, J.K., Malfatti, S., Wayne Reeve, Ardley, J, Patrick Chain, Bräu, L, Stephanie Malfatti, Melino, V, Denton, M., Chain, P., Hajnalka Kiss, Nandesena, K, Kiss, H, Yates, R, Copeland, A., Melino, V., Ivanova, N, Ravi Tiwari, Lapidus, A, Ivanova, N., Graham O’Hara, Kiss, H., Alla Lapidus, Nandesena, K., O'Hara, G, Yates, R.J., Yates, R., Julie Ardley, Kyrpides, N., Copeland, A, et al., Markowitz, V., Vanessa Melino, Reeve, W.G., O'Hara, G.W., Nolan, M., Miriam Land, Matthew Denton, Tiwari, R., Nikos Kyrpides, Matt Nolan, Tiwari, R, Reeve, W., Reeve, W, Land, M., O'Hara, G., Ron Yates, Denton, M, Kemanthi Nandesena, Howieson, J, Mavromatis, K., Ardley, J., Chain, P, Kyrpides, N, Lapidus, A., Land, M, Howieson, J.G., Malfatti, S, Markowitz, V, Bräu, L.   +68 more
core   +1 more source

Complete Genome Sequence of the Type Strain of Macrococcus canis [PDF]

, 2018
The first complete genome sequence of the recently described Macrococcus canis species has been determined for the strain KM45013T (=DSM 101690T = CCOS 969T = CCUG 68920T = CCM 8748T).
Rychener, Lorenz, Roman Pantůček, Gobeli, Stefanie, Schwendener, Sybille, Vincent Perreten, Stefanie Gobeli Brawand, Lorenz Rychener, Perreten, Vincent, Pantůček, Roman, Sybille Schwendener   +9 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient

, 2012
Schröder J, Maus I, Meyer K, et al. Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient. BMC Genomics.
Jochen Blom, Trost, Eva, Jasmin Schröder, Trost, Eva ; https://orcid.org/, Sebastian Jaenicke, Jaenicke, Sebastian, Maus Irena, Schröder Jasmin, Schneider, Jessica, Katja Meyer, Wördemann, Stephanie, Schneider Jessica, Maus, Irena, Blom Jochen, Blom, Jochen, Meyer Katja, Jessica Schneider, Andreas Tauch, Tauch Andreas, Eva Trost, Stephanie Wördemann, Meyer, Katja, Tauch, Andreas, Wördemann Stephanie, Jaenicke Sebastian, Schröder, Jasmin, Trost Eva, Irena Maus   +27 more
core   +1 more source

CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes [PDF]

, 2007
Background: The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequence tags (GSTs) for the Arabidopsis research community.
Allemeersch, Joke, De Meyer, B., Sclep Gert, Kuiper, M., Kuiper, Martin, Robin Liechti, Moreau, Yves, Reymond, Philippe, Jean-Pierre Renou, Gert Sclep, Liechti Robin, Robin Liechti, Rishikesh Bhalerao, Sclep, G., Reymond, P., Bhalerao Rishikesh, Pierre Hilson, Renou, J., Kuiper, Martin T. R ., Hilson, P., Allemeersch, J., Bhalerao, Rishikesh P., Bhalerao, Rishikesh, Renou, Jean-Pierre, Beynon Jim, Moreau, Y., Nietfeld, W., Nietfeld Wilfried, Reymond Philippe, Wilfried Nietfeld, Moreau Yves, Joke Allemeersch, Björn De Meyer, Kuiper, Martin T.R., Bhalerao, R., Philippe Reymond, Beynon, Jim, Jim Beynon, Martin TR Kuiper, De Meyer, Björn, Nietfeld, Wilfried, De Meyer Björn, Liechti, Robin, Kuiper Martin TR, Kuiper, Martin Tr, Renou Jean-Pierre, Allemeersch Joke, Gert Sclep, Sclep, Gert, Hilson Pierre, Hilson, Pierre, Beynon, J., Liechti, R., Yves Moreau   +53 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Complete genome sequence of the Medicago microsymbiont Ensifer (Sinorhizobium) medicae strain WSM419

, 2010
Ensifer (Sinorhizobium) medicae is an effective nitrogen fixing microsymbiont of a diverse range of annual Medicago (medic) species. Strain WSM419 is an aerobic, motile, non-spore forming, Gram-negative rod isolated from a M.
Land, M., Markowitz, V., Copeland, A., Gollagher, M., Dilworth, M.J., Reeve, W.G., O'Hara, G.W., Nandasena, K.G., Nolan, M., Chang, Y-J, Mavromatis, K., Ardley, J.K., Malfatti, S., Kyrpides, N, Ivanova, N., Tiwari, R., Lapidus, A., Kiss, H., Howieson, J.G., Yates, R.J., Hauser, L., Chain, P., Bräu, L.   +22 more
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