The Effects of Neurosteroids, such as Pregnenolone Sulfate and its receptor, TrpM3 in the Retina. [PDF]
Pregnenolone sulfate (PregS) is the precursor to all steroid hormones and is produced in neurons in an activity dependent manner. Studies have shown that PregS production is upregulated during certain critical periods of development, such as in the first
Webster, Corey Michael
core
State-Dependent Modulation of Gap Junction Signaling by the Persistent Sodium Current [PDF]
Thalamic neurons fluctuate between two states: a hyperpolarized state associated with burst firing and sleep spindles, and a depolarized state associated with tonic firing and rapid, reliable information transmission between the sensory periphery and ...
Julie S Haas +3 more
core +2 more sources
Regulation of connexin36 gap junction channels by n‐alkanols and arachidonic acid
Key points Under control conditions only one of ∼128 connexin (Cx)36 gap junction channels assembled in junctional plaques are open at a given time. This ratio was increased several times by short carbon chain n‐alkanols and BSA, and reduced by long carbon chain n‐alkanols.
Alina, Marandykina +4 more
openaire +3 more sources
Cx36 makes channels coupling human pancreatic β-cells, and correlates with insulin expression [PDF]
Previous studies have documented that the insulin-producing β-cells of laboratory rodents are coupled by gap junction channels made solely of the connexin36 (Cx36) protein, and have shown that loss of this protein desynchronizes β-cells, leading to ...
Berney, Thierry +15 more
core
Manipulating sleep spindles - expanding views on sleep, memory, and disease. [PDF]
Sleep spindles are distinctive electroencephalographic (EEG) oscillations emerging during non-rapid-eye-movement sleep (NREMS) that have been implicated in multiple brain functions, including sleep quality, sensory gating, learning, and memory.
Astori, S., Lüthi, A., Wimmer, R.D.
core +2 more sources
Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size. [PDF]
Yuan C +3 more
europepmc +1 more source
Cost variability, quality of care and hospitals' payment systems [PDF]
In most European countries hospitals' payment is based on a prospective payment per DRG. This article highlights the potential drawbacks of such a payment system when the regulator (the National Health Insurance) can observe neither the quality ...
Maréchal, François, Mougeot, Michel
core
Roles of connexins and pannexins in (neuro)endocrine physiology. [PDF]
International audienceTo ensure appropriate secretion in response to organismal demand, (neuro)endocrine tissues liberate massive quantities of hormone, which act to coordinate and synchronize biological signals in distant secretory and non-secretory ...
Desarménien, MG +3 more
core +5 more sources
Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels [PDF]
Aims/hypothesis: Pancreatic beta cells are connected by gap junction channels made of connexin 36 (Cx36), which permit intercellular exchanges of current-carrying ions (ionic coupling) and other molecules (metabolic coupling).
Cancela, J., Charpantier, E., Meda, P.
core
Response of electrically coupled spiking neurons: a cellular automaton approach
Experimental data suggest that some classes of spiking neurons in the first layers of sensory systems are electrically coupled via gap junctions or ephaptic interactions. When the electrical coupling is removed, the response function (firing rate {\it vs.
A. L. Hodgkin +35 more
core +1 more source

