Results 101 to 110 of about 42,495 (277)
Connexins and pannexins in neuronal development and adult neurogenesis
BMC Cell Biology, 2016 Connexins and pannexins share very similar structures and functions; they also exhibit overlapping expression in many stages of neuronal development. Here, we review evidence implicating connexin- and pannexin-mediated communication in the regulation of ...
L. A. Swayne, S. Bennett
semanticscholar +1 more source
Keratitis-ichthyosis-deafness syndrome, atypical connexin GJB2 genemutation, and peripheral T-cell lymphoma: more than a random association? [PDF]
, 2011 Keratitis-ichthyosis-deafness (KID) syndrome is a rare congenital disorder characterized by a variety of skin lesions— that is, palmoplantar keratoderma, thickening of the skin, and erythematous verrucous lesions—neurosensorial hypoacusia, and keratitis
Contini, Salvatore +6 more
core +2 more sources
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Increased hours of cochlear implant (CI) use have been shown to improve auditory and speech recognition outcomes in children with hearing loss. However, the impact of hours of CI use over time on patient‐reported functional hearing skills is unknown.
Lacey Magee +3 more
wiley +1 more source
Coordination of innate immune responses by connexins
Frontiers in ImmunologyInnate immunity comprises intricate cellular and tissue responses critical for host defense and tissue homeostasis. Intercellular communication is central to these responses and significantly influences infection, inflammatory disorders, and cancer ...
Qirou Wu +4 more
doaj +1 more source
Archives of Medical Science, 2016 Introduction: Connexin-43 (Cx43), a connexin constituent of gap junctions (GJs) is mainly expressed in bone marrow stromal cells (BMSCs) and played a important role on hematopoiesis.
Jinxiang Fu
doaj +1 more source
Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins
Frontiers in Neuroscience, 2016 Purinergic receptors play an important role in inflammation, and can be activated by ATP released via pannexin channels and/or connexin hemichannels. The purinergic P2X7 receptor (P2X7R) is of interest since it is involved in apoptosis when activated ...
E. F. Diezmos, P. Bertrand, Lu Liu
semanticscholar +1 more source
Regulation of cardiovascular connexins by mechanical forces and junctions [PDF]
, 2017 Connexins form a family of transmembrane proteins that consists of 20 members in humans and 21 members in mice. Six connexins assemble into a connexon that can function as a hemichannel or connexon that can dock to a connexon expressed by a neighbouring ...
Delmar, Mario +3 more
core
CO2-dependent opening of an inwardly rectifying K+ channel [PDF]
, 2011 CO2 chemosensing is a vital function for the maintenance of life that helps to control acid–base balance. Most studies have reported that CO2 is measured via its proxy, pH. Here we report an inwardly rectifying channel, in outside-out excised patches
Dale, Nicholas, Huckstepp, Robert T. R.
core +2 more sources
MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion
Environmental Toxicology, EarlyView.ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari +2 more
wiley +1 more source
Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43
Frontiers in Physiology, 2018 Dendritic cells (DCs) travel through lymphatic vessels to transport antigens and present them to T cells in lymph nodes. DCs move directionally toward lymphatics by virtue of their CCR7 and a CCL21 chemotactic gradient.
Richard Ruez +7 more
doaj +1 more source