Results 171 to 180 of about 1,314 (186)
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Direct cDNA cloning of novel conopeptide precursors of the O-superfamily
Peptides, 2005Conotoxins from the venom of marine cone snails (genus Conus) represent large families of proteins exhibiting a similar precursor organization, but highly diverse pharmacological activities. A directed PCR-based approach using primers according to the conserved signal sequence was applied to investigate the diversity of conotoxins from the O ...
Silke, Kauferstein +2 more
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Oxidative Folding of Conopeptides Modified by Conus Protein Disulfide Isomerase
The Protein Journal, 2017Protein disulfide isomerase is a type of enzyme that catalyses the oxidation, isomerization and reduction of disulfide bonds. Conotoxins that containing disulfide bonds are likely substrates of protein disulfide isomerise. Here, we cloned 12 protein disulfide isomerise genes from 12 different cone snail species that inhabited the sea near Sanya in ...
Lei, Wang +8 more
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Synthesis and insecticidal activity of cysteine-free conopeptides from Conus betulinus
Toxicon, 2023Bingmiao Gao
exaly
Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter
Nature Neuroscience, 2001David J. Adams +2 more
exaly