Results 151 to 160 of about 22,310 (212)

Neuroprotection of paeoniflorin as antidepressant candidate. [PDF]

Biomedicine (Taipei)
Chen YF, Chen YJ, Yang JS, Lee MM, Tsai HY.   +4 more
europepmc   +1 more source

On-Resin Acetamidomethyl (Acm) Removal and Disulfide Formation in Cysteinyl Peptides Using <i>N</i>-Chlorosuccinimide (NCS) in the Presence of Other Cys-Protecting Groups. [PDF]

Int J Mol Sci
Chakraborty A, Albericio F, de la Torre BG.   +2 more
europepmc   +1 more source

Surface-Imprinted Acrylamide Polymer-Based Reduced Graphene-Gold Sensor in Rapid and Sensitive Electrochemical Determination of αB-Conotoxin. [PDF]

Sensors (Basel)
Cao J, Li J, Yu T, Wang F.
europepmc   +1 more source

Calcium regulation of muscle spindle mechanosensory afferent function. [PDF]

Exp Physiol
Simon A, Lofthouse RA, Miti P, Giuraniuc CV, Banks RW, Bewick GS.   +5 more
europepmc   +1 more source

Cyclization of the Analgesic α-Conotoxin Vc1.1 With a Non-Natural Linker: Effects on Structure, Stability, and Bioactivity. [PDF]

J Pept Sci
Zhang Y, Tae HS, Adams DJ, Durek T, Craik DJ.   +4 more
europepmc   +1 more source

Voltage-gated calcium channels as key regulators of neuronal differentiation in the immortalized dorsal root ganglion neuronal cell line F11. [PDF]

Sci Rep
López D, Brea J, Barro M, Loza MI, Martínez AL.   +4 more
europepmc   +1 more source

Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes

Biochemical and Biophysical Research Communications, 2006
α-Conotoxin OmIA from Conus omaria is the only α-conotoxin that shows a ∼20-fold higher affinity to the α3β2 over the α6β2 subtype of nicotinic acetylcholine receptor.
Kyou-Hoon Han, Seung-Wook Chi, J Michael McIntosh   +2 more
exaly   +2 more sources

Conotoxins: Chemistry and Biology [PDF]

Chemical Reviews, 2019
The venom of the marine predatory cone snails (genus Conus) has evolved for prey capture and defense, providing the basis for survival and rapid diversification of the now estimated 750+ species. A typical Conus venom contains hundreds to thousands of bioactive peptides known as conotoxins.
Ai-Hua Jin, Markus Muttenthaler, Sebastien Dutertre, S.W.A. Himaya, Quentin Kaas, David J. Craik, Richard J. Lewis, Paul F. Alewood   +7 more
openaire   +4 more sources

Influence of ω-conotoxin on morphine analgesia and withdrawal syndrome in rats

European Journal of Pharmacology, 1992
The effect of ω-conotoxin on opiate analgesia and withdrawal syndrome was investigated in rats. ω-Conotoxin given i.c.v. and i.p. caused weak analgesia in the tail-flick test. When the toxin (20 ng/rat) was given i.c.v.
Tiziana Rubino, Gabriella Giagnoni, G Giagnoni   +2 more
exaly   +2 more sources

Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry [PDF]

Structure, 1997
Background: The venoms of Conus snails contain small, disulfide-rich inhibitors of voltage-dependent sodium channels. Conotoxin GS is a 34-residue polypeptide isolated from Conus geographus that interacts with the extracellular entrance of skeletal ...
Paul F Alewood, David Craik, D J Craik
exaly   +2 more sources