Results 21 to 30 of about 420 (147)

In vitro activities of contezolid (MRX-I) against drug-sensitive and drug-resistant Mycobacterium tuberculosis

open access: yesMicrobiology Spectrum, 2023
A novel oxazolidinone for the treatment of Mycobacterium tuberculosis has been developed, but the activity of contezolid (MRX-I) still needs to be clarified.
Huiru An   +5 more
doaj   +3 more sources

Health Technology Assessment of Oxazolidinones for MRSA-Associated Complicated Skin and Soft Tissue Infections [PDF]

open access: yesDrug Design, Development and Therapy
Yucheng Zhao, Baisen Huang, Zunchang Yang, Hongjie Kuang, Jisheng Chen Key Specialty of Clinical Pharmacy, the First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, People’s Republic of ChinaCorrespondence: Jisheng Chen, Key ...
Zhao Y, Huang B, Yang Z, Kuang H, Chen J
doaj   +2 more sources

Safety and Tolerability of Contezolid Versus Linezolid for Short-Term Treatment of Rifampicin-Resistant Pulmonary Tuberculosis: A Randomized Controlled Study [PDF]

open access: yesInfection and Drug Resistance
Jun Wang,* Yu Xue,* Wenjuan Nie, Liping Ma, Naihui Chu, Yadong Du Tuberculosis Department, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, People’s Republic of China&
Wang J, Xue Y, Nie W, Ma L, Chu N, Du Y
doaj   +2 more sources

Tuberculosis patients with special clinical conditions treated with contezolid: three case reports and a literature review

open access: yesFrontiers in Medicine, 2023
BackgroundContezolid is a novel oxazolidinone antibacterial agent, but there have been no reports of any pertinent clinical studies for the treatment of tuberculosis (TB).
Jun Wang, Liping Ma
doaj   +3 more sources

Successful Treatment of Intractable Tuberculous Peritonitis in a Woman with Chronic Kidney Allograft Dysfunction Using Contezolid Containing Regimen [PDF]

open access: yesInfection and Drug Resistance
Weijian Liu,* Liangzi Yang,* Hongjuan Qin, Peize Zhang Department of Pulmonary Medicine and Tuberculosis, The Third People’s Hospital of Shenzhen, Shenzhen, Guangdong, People’s Republic of China*These authors contributed equally to this ...
Liu W, Yang L, Qin H, Zhang P
doaj   +2 more sources

Case report: Successful treatment with contezolid in a patient with tuberculous meningitis who was intolerant to linezolid

open access: yesFrontiers in Medicine, 2023
Tuberculous meningitis (TBM) is the most common form of central nervous system tuberculosis (TB) and the most severe form of extrapulmonary TB. It often presents with non-specific symptoms initially and has a high mortality and disability rate. With good
Zhe Xu   +6 more
doaj   +3 more sources

Current Status and Perspectives of Antibacterial Agents Belonging to 2-Oxazolidinones [PDF]

open access: yesPharmaceuticals
In the last three decades, 2-oxazolidinones have emerged as an important class of inhibitors of bacterial protein synthesis, effective in the treatment of multidrug-resistant (MDR) bacterial infections. From a public health perspective, the importance of
Jessica Ceramella   +9 more
doaj   +2 more sources

Advances in Therapeutic Drug Monitoring and Pharmacokinetic Researches of Oxazolidinone Antibacterial Agents in the Elderly Patients [PDF]

open access: yesClinical Interventions in Aging
Tingting Liu,1,2,* Zeyang Li,1,2,* Ge Wei,3,* Yang Yang,1 Fang Wang,1 Yue Wang,1 Keke Kang,1 Ping Yang,1 Hongxia Li,1 Bing Liu,4 Xiangqun Fang1 1Department of Pulmonary and Critical Care Medicine, The Second Medical Center & ...
Liu T   +10 more
doaj   +2 more sources

Safety and Effectiveness of Contezolid versus Linezolid in Drug-Resistant Tuberculosis: A 12-Month Retrospective Study from China [PDF]

open access: yesInfection and Drug Resistance
Yu Xiao,* Peng-Fei Huang,* Lei Xie, Lei Gao, Yi Han, Shuang Liu, Ya-Xue Liang, Yan-Jun Xiong, Hua Wang Department of Tuberculosis, Anhui Provincial Chest Hospital (Anhui Institute of Tuberculosis Control), Hefei, Anhui, 230022, People’s ...
Xiao Y   +8 more
doaj   +2 more sources

Efficacy of Contezolid in the Treatment of Catheter-Related Bloodstream Infections Caused by Methicillin-Resistant Staphylococcus aureus in a Patient with Hepatorenal Syndrome and Acute Kidney Injury: A Case Report [PDF]

open access: yesInfection and Drug Resistance
Xiucui Zhang,* Huili Huang,* Jianrong Wang, Bo Wei Department of Infectious Disease, Changzheng Hospital, Navy Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Bo Wei ...
Zhang X, Huang H, Wang J, Wei B
doaj   +2 more sources

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