Results 151 to 160 of about 6,209 (262)

Modelado y control no lineal de un puente grúa

open access: yes
El trabajo fin de máster trata sobre el modelado y el control de un sistema altamente no lineal como es un puente grúa. En él, se habla de los aspectos fundamentales para conocer el modelado de dicho sistema, así como de diferentes formas de control del mismo.
Cabrejas Escosa, Carla   +1 more
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Cell lineage-resolved embryonic morphological map reveals signaling associated with cell fate and size asymmetry. [PDF]

open access: yesNat Commun
Guan G   +10 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum? [PDF]

open access: yesSci Rep
Guan F   +10 more
europepmc   +1 more source

Diseño, construcción y control de un péndulo invertido rotacional utilizando técnicas lineales y no lineales

open access: yes, 2009
Este trabajo presenta el desarrollo y control de un péndulo invertido rotacional (péndulo de Furuta). Un ejemplo de este tipo de sistemas son las aeronaves, vehículos espaciales, vehículos submarinos, barcos, satélites y robots construidos por barras y uniones articuladas pasivas y activas. Algunas veces, la subactuación puede ser causada por fallas en
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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