Results 161 to 170 of about 13,466 (296)

Control adaptativo de sistemas no lineales a tiempo discreto

, 1997
Este trabajo se dedica a la aplicación de técnicas adaptativas con elpropósito de resolver el problema de seguimiento de trayectorias para algunas clasesde sistemas no lineales a tiempo discreto. Se alcanza el objetivo de control por diversoscaminos. Éstos se resumen en la utilización de métodos de control adaptativoconocidos a sistemas submodelados ...
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Proton boron capture therapy: microdosimetry and treatment planning study with boron. [PDF]

Front Oncol
Yoo SH, Sedliarou I, MacDiarmid JA, Brahmbhatt H, Han S, Kim KB, Tran LT, Rosenfeld AB, Kim EH, Lin YH, Tan WS, Cheah YY, Wong RX, Looi WS, Ho S, Han KB, Yeo P, Djeng SK.   +17 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Implementación del control no lineal adaptativo en un péndulo de rueda de reacción

, 2015
El control es una de las disciplinas que en la actualidad tiene grandes ventajas y beneficios en muchos ámbitos de automatización, en las que permite optimizar los tiempos en la ejecución de una tarea específica en procesos industriales, y generando ...
Nieto Trejos, Jhon Alexánder, García Ramírez, Cesar Augusto   +1 more
core  

[Patient complaints in primary care in a Spanish region (2018-2024): A quantitative analysis]. [PDF]

Aten Primaria
Pérez-Jiménez A, Font Jiménez I, Hernández Fernández F.   +2 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Impact of acromegaly subtypes on survival: results from a large multicenter cohort. [PDF]

J Endocr Soc
Cuevas-Ramos D, Labadzhyan A, Gomez D, Fox R, Martínez-Sánchez FD, Rocha-Haro A, Gómez-Pérez FJ, Melmed S.   +7 more
europepmc   +1 more source

Control óptimo de problemas elípticos lineal-cuadráticos

, 2017
Grado en ...
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source