Results 51 to 60 of about 1,002,109 (310)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Efeito da temperatura e condições de atmosfera controlada sobre a conservação de caqui (Diospyrus kaki, L.) Effect of temperature and controlled atmosphere conditions on the storage of persimmon (Diospyrus kaki, L.)

open access: yesCiência Rural, 1995
Com o objetivo de avaliar o efeito das temperaturas de armazenamento e condições de atmosfera normal (AN) e controlada (AC) sobre as qualidades físico-químicas e organolépticas de caquis, foi conduzido um experimento no Núcleo de Pesquisa em Pós-colheita(
Auri Brackmann, Adriano Arriel Saquet
doaj   +1 more source

A passive sampling method for radiocarbon analysis of atmospheric CO2 using molecular sieve [PDF]

open access: yes, 2010
Radiocarbon (14C) analysis of atmospheric CO2 can provide information on CO2 sources and is potentially valuable for validating inventories of fossil fuel-derived CO2 emissions to the atmosphere.
Garnett, M.H., Hartley, I.P.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Pruning and Flower Thinning Influence the Storability of CH201/FRED® Pears

open access: yesAgronomy
CH201/FRED® is a novel red-blush pear cultivar with long-term storage potential and a prolonged shelf life. However, it is prone to controlled atmosphere (CA)-related disorders, particularly cavities. This study explored the impact of the balance between
Séverine Gabioud Rebeaud   +6 more
doaj   +1 more source

Atmospheric Turbulence-Controlled Cryptosystems [PDF]

open access: yesIEEE Photonics Journal, 2021
To overcome the limitations of QKD, post-quantum cryptography, and computational security-based cryptography protocols in this paper, an atmospheric turbulence-controlled cryptosystem is proposed. The proposed encryption scheme employs the traditional scheme to utilize the atmospheric turbulence as the common source of randomness only in the ...
openaire   +2 more sources

Exposure system for animals Patent [PDF]

open access: yes, 1968
System for continuous monitoring of exhalations, weighing, and cage cleaning for animal exposed to controlled atmosphere for toxic ...
Quattrone, P. D., Staley, R. W.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Gas diffusion liquid storage bag and method of use for storing blood [PDF]

open access: yes, 1979
The shelf life of stored whole blood may be doubled by adding a buffer which maintains a desired pH level. However, this buffer causes the generation of CO2 which, if not removed at a controlled rate, causes the pH value of the blood to decrease, which ...
Bank, H., Cleland, E. L.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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