Results 171 to 180 of about 3,898 (208)

Isolation and structure of a peptide toxin from the marine snail Conus magus

Archives of Biochemistry and Biophysics, 1982
Abstract A 14-residue peptide toxin has been isolated from the venom of the marine snail Conus magus. Its amino acid sequence, GlyArgCysCysHisProAlaCysGly LysAsnTyrSerCysNH2, is homologous with those of the previously described conotoxins GI, GII, and GIA from Conus geographus.
M, McIntosh, L J, Cruz, M W, Hunkapiller, W R, Gray, B M, Olivera   +4 more
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Unraveling the peptidome of the South African cone snails Conus pictus and Conus natalis

Peptides, 2013
Venoms from cone snails (genus Conus) can be seen as an untapped cocktail of biologically active compounds, being increasingly recognized as an emerging source of peptide-based therapeutics. Cone snails are considered to be specialized predators that have evolved the most sophisticated peptide chemistry and neuropharmacology system for their own ...
Steve, Peigneur, Annelies, Van Der Haegen, Carolina, Möller, Etienne, Waelkens, Elia, Diego-García, Frank, Marí, Ryno, Naudé, Jan, Tytgat   +7 more
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Piscivorous Behavior of a Temperate Cone Snail,Conus californicus

The Biological Bulletin, 2005
Most of the more than 500 species of predatory marine snails in the genus Conus are tropical or semitropical, and nearly all are thought to be highly selective regarding type of prey. Conus californicus Hinds, 1844, is unusual in that it is endemic to the North American Pacific coast and preys on a large variety of benthic organisms, primarily worms ...
Julia, Stewart, William F, Gilly
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Venomic study on cone snails (Conus spp.) from South Africa

Toxicon, 2011
From six Conus species (Conus coronatus, Conus lividus, Conus mozambicus f. lautus, Conus pictus, Conus sazanka, Conus tinianus) collected off the eastern coast of South Africa the venoms were analyzed using MALDI-TOF mass spectrometry. Between 56 and 151 molecular masses most in a range of 1000 to 2500 Da, were identified.
Kauferstein, S., Porth, C., Kendel, Y., Wunder, C., Nicke, A., Kordis, D., Favreau, P., Koua, D., Stoecklin, R., Mebs, D.   +9 more
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Pharmacological investigation of the venoms of the marine snails Conus textile and Conus geographus

Toxicon, 1962
Phrenic nerve-diaphragm preparations and isolated skeletal muscles were exposed to two Conus venoms. Rats and mice were injected intraperitoneally. Anaesthetized rats and guinea-pigs were injected intravenously, the sciatic nerve being exposed and stimulated to give a foot twitch.
Whyte J.M., Endean R.
openaire   +1 more source

Multiple genes elucidate the evolution of venomous snail-hunting Conus species

Molecular Phylogenetics and Evolution, 2009
The species-rich Cone snails (Conus sp.) are predatory, marine gastropods known for small venom peptides that are valuable for pharmacological research applications. Phylogenetic analyses with mitochondrial rRNA sequences have facilitated peptide discovery.
Hannah H, Nam, Patrice Showers, Corneli, Maren, Watkins, Baldomero, Olivera, Pradip, Bandyopadhyay   +4 more
openaire   +2 more sources

Pharmacological study on the venom of the marine snail Conus textile

Toxicon, 1981
The pharmacological effects of Conus textile venom on the rabbit aorta, the guinea-pig left atria, vas deferens and ileum, and the mouse diaphragm were examined. The venom caused a marked, transient contraction of the ileum which was abolished by atropine and tetrodotoxin.
J, Kobayashi, Y, Ohizumi, H, Nakamura, Y, Hirata   +3 more
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Diversity of A-conotoxins of three worm-hunting cone snails (Conus brunneus, Conus nux, and Conus princeps) from the Mexican Pacific coast

Peptides, 2015
Conus marine snails (∼500 species) are tropical predators that use venoms mainly to capture prey and defend themselves from predators. The principal components of these venoms are peptides that are known as "conotoxins" and generally comprise 7-40 amino acid residues, including 0-5 disulfide bridges and distinct posttranslational modifications.
Daniel, Morales-González, Ernesto, Flores-Martínez, Roberto, Zamora-Bustillos, Reginaldo, Rivera-Reyes, Jesús Emilio, Michel-Morfín, Víctor, Landa-Jaime, Andrés, Falcón, Manuel B, Aguilar   +7 more
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Venom of marine snail Conus californicus: Biochemical studies of a cholinomimetic component

Toxicon, 1979
Abstract An extract from the venom of the marine snail Conus californicus , which has cholinomimetic effects in Mercenaria heart and Aplysia central neurons, was partially purified by gel filtration and preparative silica gel and cellulose thin layer chromatography.
E J, Elliott, M A, Raftery
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Occurrence of hydroxyproline in a toxin from the marine snail Conus geographus

Archives of Biochemistry and Biophysics, 1982
Abstract A 22-residue peptide toxin from the venomous marine snail Conus geographus (L.) was found to have a most unusual amino acid composition: Lys4, Arg3, 1 2 Cys 6 , Asx2, Glx2, Thr, Ala, plus three residues of trans-4-hydroxyproline. Absence of Gly and Pro indicates that the hydroxyproline must be in sequences different from those in
B L, Stone, W R, Gray
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