Results 181 to 190 of about 3,898 (208)

Studies on the venom of the marine snail Conus californicus

Toxicon, 1963
Abstract Extracts prepared from the venom duct of the gastropod Conus californicus were lethal in mice following intravenous injection ( LD 50 approximately 2.4 mg protein/kg); symptoms included lethargy, ataxia and convulsions. No activity could be demonstrated in extracts of the venom bulb.
John A. Whysner, Paul R. Saunders
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Intraspecific variation in the venom of the vermivorous cone snail Conus vexillum

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2011
A combination of proteomic and biochemical assays was used to examine variations in the venom of Conus vexillum taken from two locations (Hurgada and Sharm El-Shaikh) in the Red Sea, Egypt. Using MALDI/TOF-MS, a remarkable degree of intra-species variation between venom samples from both locations was identified.
Mohamed A, Abdel-Rahman, Ismail M, Abdel-Nabi, Mohamed S, El-Naggar, Osama A, Abbas, Peter N, Strong   +4 more
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Conus peptides - combinatorial chemistry at a cone snail's pace.

Current opinion in drug discovery & development, 2011
Conotoxins, the disulfide-rich toxin components of venomous marine cone snails, have attracted a great deal of attention in recent years because of their demonstrated pharmacological receptor subtype selectivities and distinct potential for development as new central nervous system (CNS) therapeutics.
R M, Jones, G, Bulaj
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Putative γ-conotoxins in vermivorous cone snails: the case of Conus delessertii

Peptides, 2005
Peptide de7a was purified from the venom of Conus delessertii, a vermivorous cone snail collected in the Yucatan Channel, Mexico. Its amino acid sequence was determined by automatic Edman degradation after reduction and alkylation. The sequence shows six Cys residues arranged in the pattern that defines the O-superfamily of conotoxins, and several post-
Manuel B, Aguilar, Estuardo, López-Vera, Julita S, Imperial, Andrés, Falcón, Baldomero M, Olivera, Edgar P Heimer, de la Cotera   +5 more
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Tessulatoxin, the vasoactive protein from the venom of the marine snail Conus tessulatus

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1983
1. Tessulatoxin, a powerful vasoactive protein from the marine snail Conus tessulatus, has been purified by affinity and electrofocusing chromatography. 2. The purified protein is almost homogeneous on slab gel electrophoresis. 3. The molecular weight of tessulatoxin is 26,000: the lethal dose for the fish Rhodeus ocellatus smithi is 1 microgram/g.
J, Kobayashi, H, Nakamura, Y, Hirata, Y, Ohizumi   +3 more
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Contryphan-Vn: A Novel Peptide from the Venom of the Mediterranean Snail Conus ventricosus

Biochemical and Biophysical Research Communications, 2001
The isolation, purification, and biochemical characterization of the novel peptide Contryphan-Vn, extracted from the venom of the Mediterranean marine snail Conus ventricosus, is reported. Contryphan-Vn is the first Conus peptide described from a vermivorous species and the first purified from the venom of the single Mediterranean Conus species.
G. Raybaudi Massilia, SCHININA', Maria Eugenia, Paolo Ascenzi, Fabio Polticelli   +3 more
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Purification of the lethal fraction of the venom of the marine snail Conus californicus

Toxicon, 1966
Abstract Gel filtration of the venom of Conus californicus with Sephadex G-200 resulted in a five-fold increase in toxicity per weight of protein. The total activity recovered in the effluent fractions averaged 80 per cent of the initial actitity. Analysis of the purified venom by disc electrophoresis showed a pattern similar to that of the original ...
J A, Whysner, P R, Saunders
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A sleep-inducing peptide from the venom of the Indian cone snail Conus araneosus

Toxicon, 2015
The marine snail Conus araneosus has unusual significance due to its confined distribution to coastal regions of southeast India and Sri Lanka. Due to its relative scarceness, this species has been poorly studied. In this work, we characterized the venom of C. araneosus to identify new venom peptides. We identified 14 novel compounds.
Franklin, Jayaseelan Benjamin, Rajesh, Rajaian Pushpabai   +1 more
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PEPTIDE TOXINS FROM VENOMOUS CONUS SNAILS

Annual Review of Biochemistry, 1988
W R, Gray, B M, Olivera, L J, Cruz
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PRELIMINARY STUDIES ON THE VENOM OF THE MARINE SNAIL CONUS*

Annals of the New York Academy of Sciences, 1960
A J, KOHN, P R, SAUNDERS, S, WIENER
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