Results 81 to 90 of about 15,951 (206)

Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis [PDF]

, 2011
Oxidative stress is one of the factors that could explain the pathophysiological mechanism of inflammatory conditions that occur in cardiovascular disease (CVD) and periodontitis.
Battino, Maurizio, Bullon, Pedro, Cordero Morales, Mario David, Morillo, J.M., Quiles, José L., Ramirez Tortosa, Maria Carmen   +5 more
core  

Agrimoniin Alleviates Ferroptosis in Cold‐Stored DCD Liver Grafts Through Activation of the Nrf‐2 Pathway

Cell Proliferation, EarlyView.
Supplementing the liver preservation solution with agrimoniin protects donation after cardiac death (DCD) grafts by activating the Nrf‐2 pathway. This reduces ferroptosis, oxidative stress, and inflammation during cold storage, significantly improving graft viability.
Enqiang Chang, Xiaoting Liao, Guanghua Tao, Bijun Luo, Sheng He, Linghui Pan   +5 more
wiley   +1 more source

Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth. [PDF]

, 2015
BACKGROUND: It is well established that low birth weight and accelerated postnatal growth increase the risk of liver dysfunction in later life. However, molecular mechanisms underlying such developmental programming are not well characterized, and ...
Aiken, Ballardini, Berlanga, Breij, Cambonie, Carr, Catherine E Aiken, Choi, Denise S Fernandez-Twinn, Duberley, Faienza, Farhangi, Folch, Friedman, García-Monzón, Geerts, George, Giussani, Green, Hales, Han, Hidaka, Iain P Hargreaves, Ikematsu, Jane L Tarry-Adkins, Jiang, Josie M McConnell, Li, Liu, Lönnrot, Malgorzata S Martin-Gronert, Matteoni, Moraes, Nobili, Paik, Sanoobar, Sen, Snoeck, Sohet, Susan E Ozanne, Tarry-Adkins, Tarry-Adkins, Tarry-Adkins, Tarry-Adkins, Turunen, Viruna Neergheen, Williams, Woo, Zhou   +48 more
core   +3 more sources

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

The FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu Yang   +8 more
wiley   +1 more source

Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals

Journal of the International Society of Sports Nutrition, 2008
Background To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals.
Leutholtz Brian, Greenwood Mike, Rasmussen Christopher, Kerksick Chad, Hudson Geoffrey, Shelmadine Brian, Buford Thomas, Iosia Mike, Cooke Matthew, Willoughby Darryn, Kreider Richard   +10 more
doaj   +1 more source

Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients [PDF]

, 2016
BACKGROUND: The objective of this study was to evaluate whether the levels of coenzyme Q10 (CoQ10) in brain tissue of multiple system atrophy (MSA) patients differ from those in elderly controls and in patients with other neurodegenerative diseases ...
Bettencourt, C, Chalasani, A, Hargreaves, I, Holton, JL, Houlden, H, Kiely, AP, Neergheen, V, Schottlaender, LV   +7 more
core   +1 more source

Natural‐based antioxidants in cosmeceuticals: Extraction, bioavailability and skin ageing applications

International Journal of Cosmetic Science, EarlyView.
Natural antioxidants from plants, fruits, seeds and fungi combat ageing by neutralizing free radicals, boosting collagen and protecting against UV damage. Enhanced by green extraction and smart delivery systems, they offer powerful anti‐inflammatory and antimicrobial benefits.
Hossein Omidian, Arnavaz Akhzarmehr, Charise Dallazem Bertol   +2 more
wiley   +1 more source

Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis [PDF]

, 2019
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues.
Bullon, Pedro, Bullón Fernández, Beatriz, Miguel Rodríguez, Manuel de, Román Malo, Lourdes Victoria   +3 more
core   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

Cancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source