Results 71 to 80 of about 9,756 (188)

Combination of trimetazidine and coenzyme Q10 for the treatment of acute viral myocarditis: a systematic review and meta-analysis

Journal of Infection in Developing Countries
Introduction: Coenzyme Q10 (CoQ10) is considered to be beneficial for patients with acute viral myocarditis (AVM). In addition, trimetazidine may be also beneficial to patients with AVM by promoting cardiac energy metabolism.
Min Zeng, Zhi Chen, Yan Zhang, Yusheng Pang   +3 more
doaj   +1 more source

Ellagic Acid Enhances RSL3‐Induced Ferroptosis by Inhibiting the Nrf2/HO‐1 Signaling Pathway in Pancreatic Ductal Adenocarcinoma

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Ellagic acid potentiates RSL3‐induced ferroptosis in PANC‐1 by suppressing the Nrf2/HO‐1 antioxidant defense axis via p38 MAPK activation and Keap1 upregulation. In PDAC cells, constitutive Nrf2/HO‐1 signaling establishes a robust antioxidant shield (GPX4, HO‐1) that limits lipid ROS accumulation and confers ferroptosis resistance.
Jianhua Bai, Yihe Dai, Chern Ein Oon, Pingping Hu, Jia Luo, Jiang Han, Liman Yang, Amirabas Bostani, Zhenhao Fei, Yun Jin   +9 more
wiley   +1 more source

Quantitation, Absorption and Tissue Distribution of Coenzyme Q10 from Pak-wanban (Sauropus androgynus L. Merr.) Leaf and Its Antioxidant Activities

Walailak Journal of Science and Technology, 2019
Pak-wanban (Sauropus androgynus L. Merr.), a popular Thai vegetable, has been found to have a high content of Coenzyme Q10 (CoQ10), which is a powerful antioxidant.
Aikkarach Kettawan, kansuda wunjuntuk
doaj  

Antioxidant and neuroprotective effects of ubiquinol diacetate: Insights from SH-SY5Y cell line and Caenorhabditis elegans models of Parkinson's disease

Experimental and Molecular Pathology
Parkinson's disease (PD) is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra and the presence of misfolded α-synuclein in the brain.
Matteo Micucci, Michela Battistelli, Sabrina Burattini, Riham Osman, Francesco Onesimo, Michele Mari, Michele Retini, Ilaria Versari, Barbara Pagliarani, Andrea Tarozzi, Giovanni Zappia, Federico Gianfanti, Letizia Pruccoli   +12 more
doaj   +1 more source

Characterisation and Skin Distribution of Lecithin-Based Coenzyme Q10-Loaded Lipid Nanocapsules

Nanoscale Research Letters, 2010
The purpose of this study was to investigate the influence of the inner lipid ratio on the physicochemical properties and skin targeting of surfactant-free lecithin-based coenzyme Q10-loaded lipid nanocapsules (CoQ10-LNCs).
Yan Zemin, Zhou Huafeng, Yue Yang, Liu Guanlan, Li Yan, Zhang Jing, Duan Mingxing   +6 more
doaj   +1 more source

Higher Redox State of Coenzyme Q10 Is Associated with Higher Risk of All-Cause Mortality in a Sample from the Northern German General Population

Antioxidants
Coenzyme Q10 (CoQ10) plays an important role in human health; for example, through the antioxidant function of its reduced form (ubiquinol). As the long-term health effects of circulating CoQ10 remain largely unknown, we examined the association of total
Paula Stürmer, Katharina S. Weber, Eike A. Strathmann, Cara Övermöhle, Jakob C. Voran, Frank Döring, Matthias Laudes, Wolfgang Lieb   +7 more
doaj   +1 more source

Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice

Lipids in Health and Disease, 2018
Background Hyperlipidemia is a well-established risk factor for cardiac damage, which can lead to cardiovascular diseases. Many studies have shown that Coenzyme Q10(CoQ10) protects against cardiac damage in vivo.
Xiaoqing Zhang, Hongyang Liu, Yuhua Hao, Lulu Xu, Tiemei Zhang, Yingshu Liu, Lipeng Guo, Liyue Zhu, Zuowei Pei   +8 more
doaj   +1 more source

Blood–Brain Barrier and Neuronal Model Systems for Studying CoQ₁₀ Metabolism

Antioxidants
The disparity in outcomes between preclinical and clinical studies supplementing coenzyme Q10 (CoQ10) in neurological disorders may be a reflection of the differences in the ability of supplemental CoQ10 to access the blood–brain barrier (BBB) in rodents
David Mantle, Neve Cufflin, Mollie Dewsbury, Iain Parry Hargreaves   +3 more
doaj   +1 more source

Design of CoQ10 crops based on evolutionary history

Cell
Coenzyme Q (CoQ) is essential for energy production by mitochondrial respiration, and it is a supplement most often used to promote cardiovascular health. Humans make CoQ10, but cereals and some vegetable/fruit crops synthesize CoQ9 with a side chain of nine isoprene units.
Jing-Jing Xu, Yuan Lei, Xiao-Fan Zhang, Jian-Xu Li, Qiupeng Lin, Xiang-Dong Wu, Yu-Guo Jiang, Wenyi Zhang, Runtong Qian, Shu-Yi Xiong, Kuo Tan, Yu Jia, Qiang Zhou, Yan Jiang, Hang Fan, Yan-Bo Huang, Ling-Jian Wang, Ji-Yun Liu, Yu Kong, Qing Zhao, Lei Yang, Jinxing Liu, Yong-Hong Hu, Shuai Zhan, Caixia Gao, Xiao-Ya Chen   +25 more
openaire   +2 more sources

FSP1 reduces exogenous coenzyme Q10 and inhibits ferroptosis to alleviate intestinal ischemia–reperfusion injury

Journal of Advanced Research
Introduction: Intestinal ischemia–reperfusion injury (IRI) is a critical condition often requiring emergency intervention. Ferroptosis, a form of regulated cell death driven by phospholipid peroxidation, plays a central role in its pathogenesis ...
Tianli Shen, Xingjie Wang, Junxiang Zhang, Yuyao Lin, Lindi Cai, Kai Deng, Cancan Zhou, Guanglin Qiu, Jie Lian, Qinhong Xu, Zhengdong Jiang, Pengwei Zhao, Yunhua Wu, Shufeng Wang, Lin Fan, Xuqi Li   +15 more
doaj   +1 more source