Results 81 to 90 of about 15,919 (216)
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a model of Parkinson's disease [PDF]
, 2009 Background Parkinson's disease (PD) is the most common movement disorder. Extrapyramidal motor symptoms stem from the degeneration of the dopaminergic pathways in patient brain.
Katharina Faust +5 more
core +1 more source
Coenzyme Q 10: multiple benefits in one ingredient
Oléagineux, Corps gras, Lipides, 2011 Coenzyme Q is a lipid molecule widely diffused in nature; in humans and other mammals it is present as coenzyme Q10. (CoQ10). The first recognized role of CoQ10 was in mitochondrial bioenergetics, where it plays a central role in the production of ATP ...
Littarru Gian Paolo, Lambrechts Peter
doaj +1 more source
Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway [PDF]
, 2017 Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidation ...
Barca, Emanuele +7 more
core +1 more source
Advanced Science, Volume 13, Issue 20, 9 April 2026.Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She +14 more
wiley +1 more source
Journal of the International Society of Sports Nutrition, 2008 Background To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals.
Leutholtz Brian +10 more
doaj +1 more source
Improving the anti-ageing activity of coenzyme Q10 through protransfersome-loaded emulgel
Scientific Reports, 2022 Coenzyme Q10 (CoQ10) is a naturally produced organic molecule which acts as an antioxidant agent, including in skin anti-ageing, and plays a major role in the social determinants of health.
Qurrota Ayunin +5 more
doaj +1 more source
Disease modifying therapy for multiple system atrophy – Parkinsonian Type [PDF]
, 2017 BACKGROUND: Multiple System Atrophy –Parkinsonian Type (MSA-P) is a rare, rapidly progressive neurodegenerative disease without any current treatment.
Dwyer, Sean Sullivan
core
Evidence of oxidative stress and mitochondrial dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts: Effect of coenzyme Q10 supplementation on these parameters [PDF]
, 2017 Spinocerebellar ataxia type 2 (SCA2) is a rare neurodegenerative disorder caused by a CAG repeat expansion in the ataxin-2 gene. We show increased oxidative stress, abnormalities in the antioxidant system, changes in complexes involved in oxidative ...
Bie, AS +7 more
core +1 more source
GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer
Advanced Science, Volume 13, Issue 23, 23 April 2026.This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier +16 more
wiley +1 more source
Ferroptotic neurodegeneration and diet: a narrative review
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Dietary regimes and separate components have been reported to reduce ferroptosis by (1) altering iron metabolism, (2) increasing antioxidant defense, and (3) reducing lipid peroxidation. This ultimately leads to reduced ferroptosis and neurodegeneration.
Ximaine R. van der Burg +4 more
wiley +1 more source