DCC in the cerebral cortex is required for cognitive functions in mouse
Abstract Schizophrenia (SZ) is a highly heritable mental disorder, and genome‐wide association studies have identified the association between deleted in colorectal cancer (DCC) and SZ. Previous study has shown a lowered expression of DCC in the cerebral cortex of SZ patient.
Yun‐Qing Hu+9 more
wiley +1 more source
Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat [PDF]
There is a paucity of information on the molecular biology of aging processes in the brain. We have used biomarkers of aging (SA β-Gal, p16Ink4a, Sirt5, Sirt6, and Sirt7) to demonstrate the presence of an accelerated aging phenotype across different ...
Khojah, Sohair M.+3 more
core +2 more sources
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley +1 more source
Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]
Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina+8 more
core +4 more sources
Cranial ultrasound in neonatal brain infections
Abstract Infection of the neonatal central nervous system (CNS) can cause irreversible brain damage. Cranial ultrasound is an important neuroimaging modality in the neonatal period for detecting brain injury. Several types of organism can cause neonatal CNS infection.
Roosmarijn G. Licht‐van der Stap+26 more
wiley +1 more source
The dancing queen:explanatory mechanisms of the 'feel-good effect' in dance [PDF]
Dance is a social, creative form of human activity impacting on wellbeing through emotional involvement in active or passive participation at all levels of mastery.
Calmeiro, Luis, Jola, Corinne
core +1 more source
Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya+4 more
wiley +1 more source
Abstract Objective Deep brain stimulation of the centromedian nucleus of the thalamus (CM‐DBS) is an investigational, off‐label treatment for drug‐resistant epilepsy (DRE) in children. Although emerging evidence supports its safety and efficacy for select indications, the effect of CM‐DBS on quality of life and functional outcomes such as school ...
Karim Mithani+21 more
wiley +1 more source
Iron Deficiency-Induced Changes in the Hippocampus, Corpus Striatum, and Monoamines Levels That Lead to Anxiety, Depression, Sleep Disorders, and Psychotic Disorders. [PDF]
Shah HE+6 more
europepmc +1 more source
über Lokalisation innerhalb des Corpus striatum [PDF]
In dieser Arbeit wurde ein Fall von Tumor cerebri beschrieben, welcher langere Zeit hindurch klinisch beobachtet worden war und anatomisch kontrolliert wurde. Die wichtigste Erscheinung war das Auftreten cerebraler Blasenstorungen. Es wurde an der Hand der Literatur betont, dass diese Blasenstorungen die Folge der doppelseitigen Lasion des Corpus ...
openaire +2 more sources