Results 31 to 40 of about 56,895 (205)

Detrimental Role of Corticotropin-Releasing Factor on the Decrease of CA1 Field Potential Induced by In Vitro Ischemia in Rat Hippocampal Slices

Journal of Pharmacological Sciences, 2004
This experiment was designed to test the hypothesis that endogenous corticotropin-releasing factor (CRF) contributes to the neurodegenerative process following an ischemic insult.
Yoshifumi Kagamiishi, Tsuneyuki Yamamoto, Shigenori Watanabe   +2 more
doaj   +1 more source

Stressor- and Corticotropin releasing Factor-induced Reinstatement and Active Stress-related Behavioral Responses are Augmented Following Long-access Cocaine Self-administration by Rats [PDF]

, 2008
Rationale Stressful events during periods of drug abstinence likely contribute to relapse in cocaine-dependent individuals. Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing
AM Basso, B Costall, B Costall, B Lee, B Wang, B Wang, BA Sorg, BA Sorg, CJ Sanchez, David A. Baker, David M. Francis, DJ Lodge, EB Souza De, EP Zorrilla, Eric S. Katz, G Paxinos, HC Fox, J Liu, John R. Mantsch, Joseph P. Serge, JR Mantsch, JR Mantsch, K McFarland, L Lu, L Lu, LJMJ Vanderschuren, LM Najavits, LW Swanson, MA Sutton, MA Ungless, Michael A. Hoks, N Capriles, NE Goeders, NE Goeders, NH Mutschler, PW Kalivas, PW Kalivas, R Sinha, R Sinha, RA Fuchs, RE Sorge, RM Richter, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Pellow, S Pollandt, SH Ahmed, SH Ahmed, SH Ahmed, SH Ahmed, TE Kippin, TM Korotkova, V Deroche-Gamonet, Y Shaham, Y Zhou, Z Sarnyai, Z Sarnyai   +62 more
core   +2 more sources

Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior

Frontiers in Neuroscience, 2013
Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis.
James H Fox, Christopher A Lowry
doaj   +1 more source

Human fear acquisition deficits in relation to genetic variants of the corticotropin releasing hormone receptor 1 and the serotonin transporter. [PDF]

PLoS ONE, 2013
The ability to identify predictors of aversive events allows organisms to appropriately respond to these events, and failure to acquire these fear contingencies can lead to maladaptive contextual anxiety.
Ivo Heitland, Lucianne Groenink, Elisabeth Y Bijlsma, Ronald S Oosting, Johanna M P Baas   +4 more
doaj   +1 more source

Stress-Induced Cocaine Seeking Requires a Beta-2 Adrenergic Receptor-Regulated Pathway from the Ventral Bed Nucleus of the Stria Terminalis That Regulates CRF Actions in the Ventral Tegmental Area [PDF]

, 2014
The ventral bed nucleus of the stria terminalis (vBNST) has been implicated in stress-induced cocaine use. Here we demonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that innervate the ventral tegmental area (VTA)
Baker, David A., Gasser, Paul J, Gerndt, Clayton H., Mantsch, John R., Vranjkovic, Oliver   +4 more
core   +2 more sources

Corticotropin-Releasing Hormone: Biology and Therapeutic Opportunities

Biology, 2022
In 1981, Wylie Vale, Joachim Spiess, Catherine Rivier, and Jean Rivier reported on the characterization of a 41-amino-acid peptide from ovine hypothalamic extracts with high potency and intrinsic activity stimulating the secretion of adrenocorticotropic ...
Alessandra Caruso, Alessandra Gaetano, Sergio Scaccianoce   +2 more
doaj   +1 more source

Transcriptional regulation of corticotropin-releasing hormone gene in stress response

IBRO Reports, 2018
As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj   +1 more source

Neurobiological Mechanisms That Contribute to Stress-related Cocaine Use [PDF]

, 2014
The ability of stressful life events to trigger drug use is particularly problematic for the management of cocaine addiction due to the unpredictable and often uncontrollable nature of stress.
Ahmed, Ahmed, Ambroggi, Amphoux, Asanuma, Back, Badrinarayan, Barik, Beckerman, Beckstead, Behan, Berridge, Blacktop, Brady, Briand, Brischoux, Broadbear, Brown, Brown, Bruijnzeel, Buffalari, Butts, Campioni, Capriles, Chen, Cintra, Coffey, Conrad, Cottler, Day, de Jong, de Kloet, De La Garza, De Vries, Deroche-Gamonet, Dobi, Dong, Duan, Dumont, Duncan, Egli, Engel, Erb, Erb, Erb, Erb, Erb, Erb, Feltenstein, Forray, Fox, Fox, Galici, Gasser, Gasser, Geisler, Georges, Ghitza, Goeders, Gonzalez-Islas, Gorboulev, Graf, Graf, Gründemann, Hahn, Harfstrand, Iversen, Jayme R. McReynolds, Jennings, Jobes, John R. Mantsch, Jordan M. Blacktop, Kalivas, Kash, Kippin, Koob, Koob, Korotkova, Kreibich, Kudo, Lee, Leri, Lewis, Lodge, Lê, Mantsch, Mantsch, Mantsch, Mantsch, Mantsch, Mantsch, McEwen, McFarland, Nobis, Oleson, Oliver Vranjkovic, Orio, Ostrander, Paul J. Gasser, Preston, Rainbow, Redila, Refojo, Ribeiro Do Couto, Riegel, Robert C. Twining, Rodaros, Roitman, Rounsaville, Saal, Sanchez, Sartor, Schulkin, Seamans, Shaham, Shaham, Shaham, Shalev, Shelton, Shields, Shin, Silberman, Sinha, Sinha, Sinha, Smith, Specio, Steffensen, Tagliaferro, Tasker, Ungless, Ungless, Ungless, Van Pett, Vialou, Vranjkovic, Wanat, Wang, Wang, Wang, Wang, Ward, Wee, Wee, Wei, Wellman, Wise, Yamaguchi, Zahm, Zoli   +149 more
core   +2 more sources

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. [PDF]

, 2015
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in ...
Blasio, Angelo, Crawford, Elena, Dadgar, Jahan, De Guglielmo, Giordano, George, Olivier, Hopf, F Woodward, Janak, Patricia H, Keiflin, Ronald, Kharazia, Viktor, Maiya, Rajani, Messing, Robert O, Millan, E Zayra, Pomrenze, Matthew B, Rice, Kenner C   +13 more
core   +2 more sources

Sex differences in corticotropin releasing factor regulation of medial septum-mediated memory formation

Neurobiology of Stress, 2019
Stress can disrupt memory and contribute to cognitive impairments in psychiatric disorders, including schizophrenia and attention deficit hyperactivity disorder.
Kimberly R. Wiersielis, Attilio Ceretti, Arron Hall, Sydney T. Famularo, Madeleine Salvatore, Alexandra S. Ellis, Harah Jang, Mathieu E. Wimmer, Debra A. Bangasser   +8 more
doaj   +1 more source