Results 91 to 100 of about 1,085 (173)
Capan-1 COSMC KO cells are more susceptible to CTL-mediated killing than Capan-1 WT.
, 2013 Chromium release assay with Capan-1 WT/Cosmc KO target cells either (GILGFVFTL ) influenza peptide loaded or not. Influenza peptide primed CD8+ T cells were used as effector cells in an E∶T ratio of 4∶1.
Caroline B. Madsen (117273) +6 more
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Expression profile of Capan-1 and T47D WT and COSMC KO cells.
, 2013 Surface/non-permeabilized (Non-perm) glycoepitope and MUC1 expression of Capan-1 and T47D WT (pink) and COSMC KO (blue) cell lines as quantified by flow cytometry using HMFG-2 (MUC1), 5E10 (MUC1), 5F4 (Tn), 3F1 (STn) and 3C9 (T) Abs.
Caroline B. Madsen (117273) +6 more
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Methylation status of CpG islands in the promoter regions of Cosmc gene.
, 2015 DNA methylation levels of CpG islands in the promoter regions of Cosmc gene were detected by bisulfite-modification sequencing PCR, and high-throughput quantitative DNA methylation analysis. Samples are B lymphocytes from peripheral blood of the 3 groups
Qiang Sun (225630) +4 more
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, 2015 Pearson correlations in 3 groups (IgAN group, n = 78; other renal disease group, n = 33; healthy children group, n = 39) between (A, B, C) Cosmc DNA methylation and Cosmc mRNA expression; (D,E,F) between aberrantly glycosylated IgA1 and Cosmc mRNA ...
Qiang Sun (225630) +4 more
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Cosmc Is Silenced in Human Tn4 B Cells through Hypermethylation of the Gene Promoter
The FASEB Journal, 2012 Background Mucin‐type O‐glycosylation is regulated through core 1 β3‐galatosyltransferase (T‐synthase) and its specific molecular chaperone Cosmc. Human Cosmc is encoded by its gene on Xq24.
Tongzhong Ju +9 more
openaire +1 more source
Auswirkung einer Tn-Antigen-Expression auf das duktale Adenokarzinom des Pankreas
, 2022 In dieser Arbeit werden die Auswirkungen einer aberranten O-Glykosylierung infolge eines Cosmc-knockouts auf die Proliferation, Progression und Fähigkeit zur Metastasierung des duktalen Adenokarzinom des Pankreas (PDAC) in vivo gezeigt.
Reinecke, Maya
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Embryonic mechanisms of coronary precursor differentiation: principles for cell therapy.
, 2009 As coronárias derivam do proepicárdio, uma estrutura formada por precursores dos constituintes de vasos coronários, células endoteliais e musculares lisas (CoSMC).
Azambujá, Ana Paula +1 more
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Expression of COMSC in HUVECs and EA.hy926 cells.
, 2013 (A) Proliferating infantile hemangiomas (IHs) (n = 3 patients) express higher levels of COSMC than HUVECs (n = 3 batches).
John Huang (281422) +7 more
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Aberrant O-GaINAc glycosylation to enhance AKT/mTOR signaling in pancreatic cancer.
, 2016 Background: Immature truncated O-GalNAc glycosylation is an important feature of pancreatic ductal adenocarcinomas and is detected with high frequency in premalignant lesions.
Izbicki, Jakob R. +7 more
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, 2021 Aberrante Glykosylierung spielt bei einer Vielzahl von pathologischen Prozessen, insbesondere bei Tumorerkrankungen, eine entscheidende Rolle. Das tumorspezifische Tn-Antigen (GalNAcα1-O-Ser/Thr) konnte in unzähligen Studien bei verschiedensten ...
Neuburg, Elena
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