Results 111 to 120 of about 896,852 (301)

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Determination of phenolic content of Berberis vulgaris L. fruits harvested at different times by multivariate analysis

International Journal of Secondary Metabolite
This study focused on the levels of phenolic compounds present in the fruits of Berberis vulgaris genotypes harvested at different times and determined the relationship between the studied traits by multivariate analysis.
Tuba Bak, Berna Doğru Çokran, Levent Kırca, Turan Karadeniz   +3 more
doaj   +1 more source

Cinnamic Acid Attenuates Ethanol‐Exacerbated Hepatocyte Pyroptosis in Type 2 Diabetes via AMPK‐Mediated NLRP3/GSDMD Inhibition

Phytotherapy Research, EarlyView.
CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang, Qin Xiang, Yue Zhang, Yu Zhang, Xiangxiang Fu, Liming Tan, Yongli Zhang, Siqi Li, Dong Gong, Xu Guo, Yonghong Zhang, Li Chen, Tao Zheng, Qibin Wang   +13 more
wiley   +1 more source

Hydroxylation of p‐Coumaric Acid by Illuminated Chloroplasts [PDF]

European Journal of Biochemistry, 1975
Chloroplasts isolated from leaves of spinach‐beet (Beta vulgaris L. ssp. vulgaris) do not catalyse the hydroxylation of p‐coumaric acid in the dark unless a reductant (such as ascorbate, NADH or NADPH) is added. Superoxide dismutase has no effect on this reaction.
openaire   +2 more sources

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

The FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti, Andre Schutzer Godoy, Caio Cesar Mello Capetti, Rafaela Sachetto Fernandes, Vanessa O. A. Pellegrini, Ornella M. Ontañon, Eleonora Campos, Rodrigo V. Portugal, Igor Polikarpov   +8 more
wiley   +1 more source

Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Aldose reductase (AR) inhibitors have vital importance in the treatment and prevention of diabetic complications. In this study, rat kidney AR was purified 19.34-fold with a yield of 3.49% and a specific activity of 0.88 U/mg using DE-52 Cellulose anion ...
Zuhal Alim, Namik Kilinç, Bülent Şengül, Şükrü Beydemir   +3 more
doaj   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

International Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta, Kamilla Yamileva, Laura Punakallio, Maryam Ghanbarirad, Evgen Multia   +4 more
wiley   +1 more source

A MYB‐Related Transcriptional Module Cooperatively Represses Xylem Development in Poplar

Plant Biotechnology Journal, EarlyView.
ABSTRACT MYB transcription factors play crucial roles in regulating plant growth and development, but the functions of the MYB‐related subfamily in woody plants remain poorly understood. In this study, we characterized PagMYBR028, an MYB‐related transcription factor from poplar ‘84 K’ (Populus alba × Populus glandulosa), which was predominantly ...
Gaofeng Fan, Jiahui Jiang, Zihan Cheng, Feixiang Ma, Zhanling Sun, Zelin Li, Yu Qi, Guanzheng Qu, Tingbo Jiang   +8 more
wiley   +1 more source

The isolation of carboxylic acids from the flowers of Delphinium formosum

, 2001
From the flowers of Delphinium formosum Boiss. et Huet. (Ranunculaceae) trans-aconitic. p-hydroxybenzoic, p-coumaric, caffeic and chlorogenic acids were isolated and identified.
Kucukislamoglu, M, Ozden, S, Durust, N, Umur, E, Durust, Y   +4 more
core   +1 more source

Distinct deposition of ester-linked ferulic and p-coumaric acids to the cell wall of developing sorghum internodes. [PDF]

Plant Biotechnol (Tokyo), 2020
Sato-Izawa K, Ito M, Nuoendagula, Kajita S, Nakamura SI, Matsumoto T, Ezura H.   +6 more
europepmc   +1 more source