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The Recombinant Viral Capsid Protein rVP1 Induces Protective Immunity Against Coxsackievirus B3 (CVB3) Lethal Challenges in Balb/c Mouse Model. [PDF]
Vaccines (Basel)Ben M'hadheb M +4 more
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Combating coxsackievirus B infections
Reviews in Medical Virology, 2022AbstractCoxsackieviruses B (CVB) are small, non‐enveloped, single‐stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild symptoms to severe acute and chronic pathologies such as cardiomyopathy and type 1 diabetes.
Abdulaziz Alhazmi +6 more
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Antiviral Research, 2009
Coxsackievirus B3 (CVB-3) is a major causative agent of chronic heart muscle infections. The present study describes a cell culture system with an ongoing virus infection to evaluate two novel inhibitory strategies, either individually or combined: (1) RNA interference (RNAi) to degrade cytoplasmatic CVB-3 RNA and (2) a vector-delivered soluble variant
Sandra Pinkert +2 more
exaly +3 more sources
Coxsackievirus B3 (CVB-3) is a major causative agent of chronic heart muscle infections. The present study describes a cell culture system with an ongoing virus infection to evaluate two novel inhibitory strategies, either individually or combined: (1) RNA interference (RNAi) to degrade cytoplasmatic CVB-3 RNA and (2) a vector-delivered soluble variant
Sandra Pinkert +2 more
exaly +3 more sources
Virology, 1987
The entire nucleotide sequence of the coxsackievirus B3 strain Nancy (CB3) genome has been determined from cDNA. The genome is 7396 nucleotides long, and encodes a 2185 amino acid long polyprotein. It exhibits the same gene organization as other enterovirus genomes.
A M, Lindberg +2 more
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The entire nucleotide sequence of the coxsackievirus B3 strain Nancy (CB3) genome has been determined from cDNA. The genome is 7396 nucleotides long, and encodes a 2185 amino acid long polyprotein. It exhibits the same gene organization as other enterovirus genomes.
A M, Lindberg +2 more
openaire +2 more sources
Coxsackievirus-Induced Pancreatitis
Viral Immunology, 2004In humans, infections with the group B coxsackieviruses (CVBs) range from asymptomatic infections to chronic, debilitating diseases. The CVBs are associated with chronic inflammatory diseases of the pancreas, heart, and central nervous system. A major focus in CVB pathogenesis is to understand the mechanisms by which these viruses cause acute diseases ...
Sally, Huber, Arlene I, Ramsingh
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Coxsackievirus in an Infant Chimpanzee
Journal of Medical Primatology, 1978Coxsackie B viruses may cause a severe, often fatal, illness in newborn and infant human subjects. As recorded in this case, infant chimpanzees respond similarly to Coxsackie B-5 virus.
M E, Kelly +3 more
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Genetics of Coxsackievirus Virulence
1997The first reported isolate of the coxsackieviruses occurred in the upstate New York town of Coxsackie (Dalldorf and Sickles 1948). By the mid-late 1950s (Dalldorf 1955), the coxsackie B viruses (CVBs) had been shown to be agents of severe human inflammatory heart muscle disease (myocarditis) (Montgomery et al. 1955; Gear et al. 1956; Javett et al. 1956;
N M, Chapman, A I, Ramsingh, S, Tracy
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The Structure of Coxsackievirus B3
1997Picornaviruses are small, nonenveloped, icosahedral viruses. The mature virions are approximately 300 A in diameter and the interior of the capsid shell is packed with single-stranded plus sense RNA (Mw ∼ 8×106 Daltons) (Rueckert 1990). The virus capsid is composed of 60 protomers, each consisting of one copy of the viral proteins VP1, VP2, VP3 and VP4
J K, Muckelbauer, M G, Rossmann
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Coxsackievirus and Congenital Malformation
JAMA: The Journal of the American Medical Association, 1967To the Editor:— I have read with particular interest the communication by Brown and Evans, "Serologic Evidence of Coxsackievirus Etiology of Congenital Heart Disease" (199: 183, 1967), because we have found a possible relation between the infections of coxsackievirus B during pregnancy and fetal deaths.
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The Coxsackievirus and Adenovirus Receptor
2008The coxsackievirus and adenovirus receptor (CAR) has been studied extensively since its identification and isolation in 1997. The CAR is an immunoglobulin superfamily protein with two extracellular Ig-like domains, a single membrane-spanning sequence, and a significant cytoplasmic domain.
P, Freimuth, L, Philipson, S D, Carson
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