Results 191 to 200 of about 18,104 (240)

Phosphorylation of S-S-S Motif in Nuclear Export Protein (NEP) Plays a Critical Role in Viral Ribonucleoprotein (vRNP) Nuclear Export of Influenza A and B Viruses. [PDF]

Adv Sci (Weinh)
Liu X, Yang C, Lin X, Sun X, Chen H, Zhang Q, Jin M.   +6 more
europepmc   +1 more source

PTM-centered therapy in malignant tumors: A new story of colchicine. [PDF]

Acta Pharm Sin B
Huang M.
europepmc   +1 more source

Breaking barriers: Respiratory viral strategies targeting the host's nuclear pore complex and nuclear transport pathways. [PDF]

Mol Biol Cell
Udi Y, Aitchison JD, Rout MP, Obado S.
europepmc   +1 more source

Mondo family proteins in diabetes. [PDF]

Front Endocrinol (Lausanne)
Barodia SK, Grant MB, Gorbatyuk MS.
europepmc   +1 more source

Viral interference of nucleocytoplasmic transport. [PDF]

J Biol Chem
Chien CY, Mobbs GW, Ehrenkranz J, Hoelz A.   +3 more
europepmc   +1 more source

YAP/TAZ: An epitome of tumorigenesis. [PDF]

Cancer Lett
Mukherjee S, Warden EA, Zhang J.
europepmc   +1 more source

The Potential of Nuclear Pore Complexes in Cancer Therapy. [PDF]

Molecules
Zaitsava H, Gachowska M, Bartoszewska E, Kmiecik A, Kulbacka J.   +4 more
europepmc   +1 more source

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Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors.

Journal of Medicinal Chemistry, 2023
Cancer cells frequently utilize elevated nuclear export to escape tumor suppression and gain proliferative advantage. Chromosome Region Maintenance 1 (CRM1/XPO1) mediates macromolecule nuclear export and plays an important role in tumorigenesis and ...
Lunan Jian, Robert Zscherp, U. Beutling, Xiaofei Shen, Shiyang Xu, Xia Zhang, M. Brönstrup, Philipp Klahn, Qingxiang Sun   +8 more
semanticscholar   +3 more sources

Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1.

Journal of Medicinal Chemistry, 2021
Nuclear export factor chromosome region maintenance 1 (CRM1) is an attractive anticancer and antiviral drug target that spurred several research efforts to develop its inhibitor.
Y. Lei, Qi An, Xiaofei Shen, Min Sui, Chungen Li, Da Jia, Youfu Luo, Qingxiang Sun   +7 more
semanticscholar   +1 more source