Results 11 to 20 of about 2,727 (153)
Metabolic engineering of Yarrowia lipolytica for the production and secretion of the saffron ingredient crocetin [PDF]
Biotechnology for Biofuels and BioproductsBackground Crocetin is a multifunctional apocarotenoid natural product derived from saffron, holding significant promises for protection against various diseases and other nutritional applications.
Tingan Zhou +5 more
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Crocetin Improves Dengue Virus-Induced Liver Injury
Viruses, 2020 Dengue virus (DENV) infection is one of the most widespread mosquito-borne viral infections. Liver injury is commonly observed in severe DENV infection, and the present study aimed to examine the efficacy of crocetin treatment in an immunocompetent mouse
Gopinathan Pillai Sreekanth +3 more
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Parabens as Agents for Improving Crocetin Esters’ Shelf-Life in Aqueous Saffron Extracts [PDF]
Molecules, 2009 The effect of parabens on the shelf-life of crocetin esters and picrocrocin in aqueous saffron solutions was studied. Degradation of saffron crocetin esters fits a first-order kinetics model, and the results indicated that the crocetin (β-D-glucosyl)-(β ...
Magdalena Martínez Tomé +5 more
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Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae
Microbial Cell Factories, 2017 Background Due to excellent performance in antitumor, antioxidation, antihypertension, antiatherosclerotic and antidepressant activities, crocetin, naturally exists in Crocus sativus L., has great potential applications in medical and food fields ...
Fenghua Chai +7 more
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Parkinson's Disease, 2020 Parkinson’s disease (PD) is the second most common neurodegenerative disease. Crocetin, derived from saffron, exerts multiple pharmacological properties, such as anti-inflammatory, antioxidant, antifatigue, and anticancer effects.
Na Dong +3 more
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Crocetin Activates Foxp3 Through TIPE2 in Asthma-Associated Treg Cells
Cellular Physiology and Biochemistry, 2015 Background/Aims: Regulatory T cells (Treg) are critical regulators of asthma. Crocetin is isolated from Chinese herb saffron and is a natural carotenoid dicarboxylic acid with anti-inflammatory potential.
Jurong Ding +3 more
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Biomedical and Biotechnology Research Journal, 2022 Background: Crocetin, an active constituent derived from Crocus sativus L. and Gardenia jasminoides, has shown to have multiple pharmacological activities such as memory booster, anti-oxidants, anti-inflammatory, and neuroprotective actions.
Dhanashree Sharadchandra Kherade +3 more
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Crocetin attenuates spared nerve injury-induced neuropathic pain in mice
Journal of Pharmacological Sciences, 2017 Crocetin is the main component of saffron and exhibits anti-oxidative and anti-inflammatory effects. Neuroinflammation and oxidative stress have been recognized to play a crucial role in the pathogenesis of neuropathic pain. We investigated the effect of
Xiaolei Wang +4 more
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Iodine-induced synthetic method and pharmacokinetic study of cis- and trans-crocetin [PDF]
Frontiers in PharmacologyObjective:This experiment aimed to obtain the relatively rare cis-crocetin isomer from natural plants, which predominantly exist in the more stable all-trans configuration.
Boshen Li +18 more
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Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice
Clinics, 2013 OBJECTIVE: To investigate the antifibrotic effects of crocetin in scleroderma fibroblasts and in sclerotic mice. METHODS: Skin fibroblasts that were isolated from three systemic scleroderma (SSc) patients and three healthy subjects were treated with ...
Yinghua Song, Lubing Zhu, Ming Li
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