Results 21 to 30 of about 2,727 (153)
The effects of crocetin, extracted from saffron, in chemotherapy against the incidence of multiple drug resistance phenotype [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Crocetin, one of the main substances of saffron extract, has anti-cancer effects. Drug resistance proteins (e.g. MRP1 and MRP2) are important reasons for the failure of cancer therapy.
Navid Neyshaburinezhad +5 more
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Processing-induced changes in neuroprotective components and mechanisms of gardeniae fructus: integrating UPLC-Q-TOF-MS/MS, network pharmacology, and in vitro analysis [PDF]
Bioresources and BioprocessingObjective Gardeniae Fructus (GF), the dried fruit of Gardenia jasminoides J. Ellis, has been used in East Asian medicine for centuries. Its carbonized form, Gardeniae Fructus Carbonisatus (GFC), is produced through processing, yet the effects of this ...
Le Sun +9 more
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Gene Expression Profiling and Biofunction Analysis of HepG2 Cells Targeted by Crocetin
Mediators of Inflammation, 2021 Crocetin is a carotenoid extracted from Gardenia jasminoides, one of the most popular traditional Chinese medicines, which has been used in the prevention and treatment of various diseases.
Yi-Ling Wen +5 more
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Antibiofilm activity of carotenoid crocetin against Staphylococcal strains [PDF]
Frontiers in Cellular and Infection MicrobiologyStaphylococcus aureus and Staphylococcus epidermidis stand as notorious threats to human beings owing to the myriad of infections they cause. The bacteria readily form biofilms that help in withstanding the effects of antibiotics and the immune system ...
Saurav Paramanya +2 more
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Crocetin shifts autophagic cell survival to death of breast cancer cells in chemotherapy
Tumor Biology, 2017 The chemotherapy with fluorouracil is not always effective, in which some breast cancer cells may survive the fluorouracil treatment through enhanced autophagy.
Ailian Zhang, Jincheng Li
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Cancer Cell International, 2017 Background More than 400,000 patients die from esophageal cancer annually. Considerable efforts have been made to develop new and effective treatments, one of which is directed toward herbal medication.
Sheng Li +5 more
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Complete microbial synthesis of crocetin and crocins from glycerol in Escherichia coli
Microbial Cell FactoriesBackground Crocin, a glycosylated apocarotenoid pigment predominantly found in saffron, has garnered significant interest in the field of biotechnology for its bioactive properties.
Jun Ho Lee +3 more
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Frontiers in Nutrition, 2022 Crocetin glycosides such as crocin are noted as functional food materials since the preventive effects of crocin have been reported against chronic disease and cancer.
Kazutoshi Shindo +15 more
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Frontiers in Bioengineering and Biotechnology, 2020 Crocetin is a plant natural product with broad medicinal applications, such as improvement of sleep quality and attenuation of physical fatigue. However, crocetin production using microbial cell factories is still far from satisfaction, probably due to ...
Tengfei Liu +10 more
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Frontiers in Pharmacology, 2021 Crocetin and crocin are two important carotenoids isolated from saffron (Crocus sativus L.), which have been used as natural biomedicines with beneficial effects for improving the suboptimal health status associated with abnormal angiogenesis.
Chen Zhao +7 more
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