Results 51 to 60 of about 2,727 (153)
Evaluation of the antidepressant-like effects of acute and sub-acute administration of crocin and crocetin in mice [PDF]
Avicenna Journal of Phytomedicine, 2015 Objective: The present study was designed to investigate the putative antidepressant effects of crocin and crocetin, two major active ingredients of Crocus sativus L.
Bahareh Amin +2 more
doaj
Construction of Escherichia coli cell factories for crocin biosynthesis
Microbial Cell Factories, 2019 Background Crocin is a carotenoid-derived natural product found in the stigma of Crocus spp., which has great potential in medicine, food and cosmetics.
Wen Wang +8 more
doaj +1 more source
SIRT Family: Biological Functions and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang +9 more
wiley +1 more source
ROS-scavenging and Anti-tyrosinase Properties of Crocetin on B16F10 Murine Melanoma Cells
, 2018 Background: Crocus sativus (Iridaceae) has been traditionally used in the Iranian folk medicine and as a culinary additive. Major components of the plant that are responsible for biological properties are saffranal, crocin, picrocrocin and crocetin ...
Javad Baharara +7 more
core +1 more source
Frontiers in Pharmacology, 2018 Crocetin (apo carotenoid dicarboxylic acid) is a common constituent of saffron. Its importance is well documented in Chinese medicine. Some studies have reported the inhibitory effect on inflammation in rats.
Yi Li, Rajat Kakkar, Jian Wang
doaj +1 more source
Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease
Food Science &Nutrition, Volume 14, Issue 7, July 2026.This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley +1 more source
The effects of crocetin on oxidative stress induced ARPE-19 cells by H2O2*
, 2023 The anti-apoptotic and antioxidant effects of crocetin was aimed to investigate on the oxidative damage model of ARPE-19 cells. The oxidative damage in ARPE cells was developed by H2O2 treatment at 800 mu M.
Tokuc, Ecem +5 more
core +1 more source
Heliyon, 2020 A coronavirus identified as COVID-19 is the reason for an infection outbreak which is started in December 2019. NO completely effective drugs and treatments are not recognized for this virus.
Azadeh Kordzadeh +2 more
doaj +1 more source
Reactive Oxygen Species‐Induced Damage in Cryopreserved Bovine Sperm: Mitigation Strategies
Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.Cryopreservation of bovine sperm results in overproduction of ROS due to osmotic pressure variations, ice crystals and dysfunction of mitochondria, which causes lipid peroxidation, fragmentation of DNA, protein damage and ultimately decline of post‐thaw sperm quality.
Mst. Mahomudha Akhtar +4 more
wiley +1 more source
Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
Immunity & Ageing, 2018 Background Crocetin, an agent derived from saffron, has multiple pharmacological properties, such as neuroprotective, anti-oxidant, and anti-inflammatory actions. These properties might benefit the treatment of Alzheimer’s disease (AD).
Jin Zhang +3 more
doaj +1 more source