Results 51 to 60 of about 993 (143)
Crocins for Ischemic Stroke: A Review of Current Evidence [PDF]
, 2022 Crocins (CRs) and the related active constituents derived from Crocus sativus L. (Saffron) have demonstrated protective effects against cerebral ischemia and ischemic stroke, with various bioactivities including neuroprotection, anti-neuroinflammation ...
Zhou, Xian (R17201) +11 more
core +1 more source
ABCC transporters mediate the vacuolar accumulation of crocins in saffron stigmas
, 2019 Compartmentation is a key strategy enacted by plants for the storage of specialized metabolites. The saffron spice owes its red color to crocins, a complex mixture of apocarotenoid glycosides that accumulate in intracellular vacuoles and reach up to 10 ...
Pietrella, M +29 more
core +2 more sources
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
An Updated Review on the Neuroprotective Constituents of Genus Gardenia [PDF]
Archives of Pharmaceutical Sciences Ain Shams UniversityCentral Nervous System (CNS) disorders include many diseases with different symptoms and causes. According to the American Psychiatric Association (APA), these disorders are classified into several categories according to the disease‘s etiology and ...
Mohga A. Zedan +3 more
doaj +1 more source
Molecules, 2022 Saffron is a very high value-added ingredient used in the food supplement market and contains a high level of safranal. Adding synthetic safranal to saffron, which is significantly cheaper, and falsifying the origin of saffron may represent recurrent ...
Benjamin Moras +6 more
doaj +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li +14 more
wiley +1 more source
, 2018 Crocus sativus L., is a plant cultivated in many countries of the world. Crocins are among the active constituents of C. sativus and their implication in cognition has been proposed. The present study was designed to investigate in the rat the effects of
Pitsikas N., Tarantilis P.A.
core +1 more source
Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential
Phytotherapy Research, EarlyView.Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi +5 more
wiley +1 more source
Agricultural &Environmental Letters, Volume 11, Issue 2, December 2026.Reduced bioaccumulation of PQ and GLY by saffron extract in Common carp (Cyprinus carpio) tissues Abstract Herbicides such as paraquat (PQ) and glyphosate (GLY) pose ecological and public health risks because of their persistence, bioaccumulation, and toxicity to aquatic organisms. This study evaluated whether aqueous saffron extract (Crocus sativus L.)
Hossein Hammami, Javad Kharkan
wiley +1 more source