Results 91 to 100 of about 6,688,450 (306)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A Plasmodium Cross-Stage Antigen Contributes to the Development of Experimental Cerebral Malaria

open access: yesFrontiers in Immunology, 2018
Cerebral malaria is a complex neurological syndrome caused by an infection with Plasmodium falciparum parasites and is exclusively attributed to a series of host–parasite interactions at the pathological blood-stage of infection.
Priyanka Fernandes   +14 more
doaj   +1 more source

Portrait of Jessie Cross, Stan's wife, ca. 1920 [picture] /

open access: yes, 1920
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross Stan's wife"--In ink, on verso.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core  

From Theses and Dissertations to ETD: Retrospective Digitization and New Forms of Scholarship [PDF]

open access: yes, 2014
Presentation for the 2014 Cross Timbers Library Collaborative (CTLC) Annual Conference. This presentation discusses electronic theses and dissertations (ETDs) and retrospective digitization and new forms of ...
Alemneh, Daniel Gelaw   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Synthetic hemozoin as a nanocarrier for cross-presentation

open access: yesImmunobiology
It is known that conventional antigen presentation involves phagocytosis of antigens followed by its internalization in endocytic compartments and presentation of epitopes through MHC class II molecules for CD4 T cells. However, since 1976 a cross-presentation pathway has been studied, in which CD8 T cells are activated via MHC class I with antigens ...
Letícia Torres-Dias   +7 more
openaire   +3 more sources

Texas Documents and Government Publications available in The Portal to Texas History [PDF]

open access: yes, 2014
Presentation for the 2014 Cross Timbers Library Collaborative (CTLC) Annual Conference. This presentation discusses Texas documents and government publications available in The Portal to Texas ...
Sittel, Robbie
core  

Deciphering the role of DC subsets in MCMV infection to better understand immune protection against viral infections

open access: yesFrontiers in Microbiology, 2014
Infection of mice with murine cytomegalovirus (MCMV) recapitulates many physiopathological characteristics of human CMV infection and enables studying the interactions between a virus and its natural host.
Marc eDALOD   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Things that make Stan cross [picture] : contending with the county council /

open access: yes, 1900
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; "Stan Cross"--In ink, lower right. "Page 5"--In ink, on note attached to verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at: http://nla ...
Cross, Stan, 1888-1977.
core  

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