Results 91 to 100 of about 6,252,002 (304)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Frontiers in Microbiology, 2014 Infection of mice with murine cytomegalovirus (MCMV) recapitulates many physiopathological characteristics of human CMV infection and enables studying the interactions between a virus and its natural host.
Marc eDALOD +3 more
doaj +1 more source
Jessie Cross on park bench, ca. 1924 [picture] /
, 1924 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross taken 1915"--In ink on verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Synthetic hemozoin as a nanocarrier for cross-presentation
ImmunobiologyIt is known that conventional antigen presentation involves phagocytosis of antigens followed by its internalization in endocytic compartments and presentation of epitopes through MHC class II molecules for CD4 T cells. However, since 1976 a cross-presentation pathway has been studied, in which CD8 T cells are activated via MHC class I with antigens ...
Letícia Torres-Dias +7 more
openaire +3 more sources
Modes of antigen presentation by lymph node stromal cells and their immunological implications
Frontiers in Immunology, 2015 Antigen presentation is no longer the exclusive domain of cells of hematopoietic origin. Recent works have demonstrated that lymph node stromal cell (LNSC) populations such as fibroblastic reticular cells, lymphatic and blood endothelial cells not only ...
Sachiko eHirosue, Juan eDubrot
doaj +1 more source
Things that make Stan cross [picture] : what makes inflation? /
, 1900 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower right. "Page 5"--In ink, on note attached to verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at ...
Cross, Stan, 1888-1977.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Frontiers in Immunology, 2012 Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors.
Annabell eBachem +12 more
doaj +1 more source
Portrait of Jessie Cross, Stan's wife, ca. 1920 [picture] /
, 1920 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross Stan's wife"--In ink, on verso.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core