Results 81 to 90 of about 6,688,450 (306)
Tumor antigen cross-presentation and the dendritic cell: Where it all begins? [PDF]
, 2010 Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that are critical for the generation of effective cytotoxic T lymphocyte (CTL) responses; however, their function and phenotype are often defective or altered in tumor-bearing hosts ...
McDonnell, A.M. +2 more
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Langerin+CD8+ Dendritic Cells in the Splenic Marginal Zone: Not So Marginal After All
Frontiers in Immunology, 2019 Dendritic cells (DC) fulfill an essential sentinel function within the immune system, acting at the interface of innate and adaptive immunity. The DC family, both in mouse and man, shows high functional heterogeneity in order to orchestrate immune ...
Ronald A. Backer +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Wally and the Major [picture] : cross purposes /
, 1958 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/47"--Lower right. "5496 Mon Mar 10 Cross Purposes"--In ink, right margin; "5419"--In ink, upper right corner; "11"--In pencil, upper left corner.; Also ...
Cross, Stan, 1888-1977.
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Salmonella modulates B cell biology to evade CD8+ T cell-mediated immune responses
Frontiers in Immunology, 2014 Although B cells and antibodies are the central effectors of humoral immunity, B cells can also produce and secrete cytokines and present antigen to helper T cells.
Marcela eLopez-Medina +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Creating Value Beyond the Library: Best Practices for Embedded Librarianship [PDF]
, 2013 Presentation for the 2013 Cross Timbers Library Collaborative (CTLC) Conference.
O'Toole, Erin +2 more
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Spatio-temporal regulation of Hsp90-ligand complex leads to immune activation.
Frontiers in Immunology, 2016 Hsp90 is the most abundant cytosolic HSP and is known to act as a molecular chaperone. We found that an Hsp90-cancer antigen peptide complex was efficiently cross-presented by human monocyte-derived dendritic cells and induced peptide-specific cytotoxic ...
Yasuaki eTamura +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Jessie Cross on park bench, ca. 1924 [picture] /
, 1924 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross taken 1915"--In ink on verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
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