Results 151 to 160 of about 35,250 (189)
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Toxicon, 2004
In Brazil, the Crotalus durissus terrificus subspecie is the most studied, particularly concerning its crotoxin. Crotoxin is the major toxic component of the South American rattlesnake Crotalus durissus venom. It is composed of two different subunits, CA called crotapotin and CB weakly toxic phospholipase A2 with high enzymatic activity. In this paper,
A, Rangel-Santos +5 more
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In Brazil, the Crotalus durissus terrificus subspecie is the most studied, particularly concerning its crotoxin. Crotoxin is the major toxic component of the South American rattlesnake Crotalus durissus venom. It is composed of two different subunits, CA called crotapotin and CB weakly toxic phospholipase A2 with high enzymatic activity. In this paper,
A, Rangel-Santos +5 more
openaire +2 more sources
Crotalus durissus terrificus snake venom regulates macrophage metabolism and function
Journal of Leukocyte Biology, 2001Abstract In the present study, we examined the effect of Crotalus durissus terrificus venom on rat macrophage metabolism and function. Two hours after subcutaneous injection of the venom, peritoneal resident (unstimulated), elicited (thioglycollate-stimulated), and activatedMycobacterium bovis strain bacille Calmette Guérin (BCG ...
S C, Sampaio +4 more
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Gyroxin, a toxin from the venom of Crotalus durissus terrificus, is a thrombin-like enzyme
Toxicon, 1988We report a simple method for the isolation of gyroxin, a protein from the venom of the South American rattlesnake Crotalus durissus terrificus. The intravenous injection of gyroxin into mice produces temporary episodes characterized by opisthotonos and rotations around the long axis of the animal.
G, Alexander +3 more
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Purification of gyroxin from a South American rattlesnake (Crotalus durissus terrificus) venom
Toxicon, 1980Abstract Gyroxin, a non-lethal toxin from Crotalus durissus terrificus venom was isolated by a procedure involving two chromatographies on Sephadex G-75 at pH 4·0; ion exchange chromatography on CM-Sephadex C-50 at pH 3·5 and chromatography on Sephadex G-75 at pH 4·0.
C, Seki, J C, Vidal, A, Barrio
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Toxicon, 2017
Small membranous vesicles are small closed fragments of membrane. They are released from multivesicular bodies (exosomes) or shed from the surface membrane (microvesicles). They contains various bioactive molecules and their molecular composition varies depending on their cellular origin.
Andréia Souza-Imberg +4 more
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Small membranous vesicles are small closed fragments of membrane. They are released from multivesicular bodies (exosomes) or shed from the surface membrane (microvesicles). They contains various bioactive molecules and their molecular composition varies depending on their cellular origin.
Andréia Souza-Imberg +4 more
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Toxicon, 2000
The venom of South American rattlesnake Crotalus durissus terrificus is very toxic but poorly immunogenic and it has an immunosuppressive ability. The heating of venom at 56, 70 or 100 degrees C for 30 min caused a diminution in the lethal, phospholipase A(2) and myotoxic activities.
A C, Rangel-Santos, I, Mota
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The venom of South American rattlesnake Crotalus durissus terrificus is very toxic but poorly immunogenic and it has an immunosuppressive ability. The heating of venom at 56, 70 or 100 degrees C for 30 min caused a diminution in the lethal, phospholipase A(2) and myotoxic activities.
A C, Rangel-Santos, I, Mota
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Myocardial damage induced by tropical rattlesnake (Crotalus durissus terrificus) venom in rats
Cardiovascular Pathology, 1993This article describes the light and electron microscopic appearance of the rat myocardium at various time intervals after the administration of Crotalus durissus terrificus venom by intraperitoneal route. The crotalid envenomation produced small foci of myocardial necrosis scattered throughout the base of the ventricles.
F, de Paola, M A, Rossi
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Toxicon : official journal of the International Society on Toxinology, 1994
The biological activities of 'yellow' and 'white' venom of a rattlesnake Crotalus durissus ruruima Hoge, 1965, found in the savanna-like vegetation (cerrado) of northern Brazil (Roraima) and Venezuela have been studied, and compared to the reference Crotalus durissus terrificus venom. The lethal activity of venoms depended on the inoculation route. The
M C, Dos Santos +3 more
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The biological activities of 'yellow' and 'white' venom of a rattlesnake Crotalus durissus ruruima Hoge, 1965, found in the savanna-like vegetation (cerrado) of northern Brazil (Roraima) and Venezuela have been studied, and compared to the reference Crotalus durissus terrificus venom. The lethal activity of venoms depended on the inoculation route. The
M C, Dos Santos +3 more
openaire +2 more sources
Toxicon, 1999
Crotalus durissus terrificus venom (CDT venom) was irradiated with four different doses of gamma rays (2, 3, 5 and 10 kGy) from a 60Co source and their structural, toxic and immunogenic properties were analysed. Venom irradiated with 2 and 3 kGy were, respectively, 2.7 and 13.5 times less toxic than the native one, whereas the 5 or 10 kGy irradiated ...
P B, Clissa +2 more
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Crotalus durissus terrificus venom (CDT venom) was irradiated with four different doses of gamma rays (2, 3, 5 and 10 kGy) from a 60Co source and their structural, toxic and immunogenic properties were analysed. Venom irradiated with 2 and 3 kGy were, respectively, 2.7 and 13.5 times less toxic than the native one, whereas the 5 or 10 kGy irradiated ...
P B, Clissa +2 more
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Toxicon, 2003
Previous work of our group demonstrated that Crotalus durissus terrificus venom has a dual effect on macrophage function: it inhibits spreading and phagocytosis and stimulates hydrogen peroxide and nitric oxide production, antimicrobial activity and glucose and glutamine metabolism of these cells.
S C, Sampaio +6 more
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Previous work of our group demonstrated that Crotalus durissus terrificus venom has a dual effect on macrophage function: it inhibits spreading and phagocytosis and stimulates hydrogen peroxide and nitric oxide production, antimicrobial activity and glucose and glutamine metabolism of these cells.
S C, Sampaio +6 more
openaire +2 more sources