Results 71 to 80 of about 1,795 (192)

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source

Crotalus durissus collilineatus Venom Induces TNF‐α and IL‐10 Production in Human Peripheral Blood Mononuclear Cells

International Scholarly Research Notices, Volume 2014, Issue 1, 2014., 2014
Snake venom has been the subject of numerous studies in an attempt to find properties and biological effects that may be beneficial to man. In this study we evaluated in vitro the effects of Crotalus durissus terrificus (Cdt) and Crotalus durissus collilineatus (Cdc) venom in human peripheral blood mononuclear cells (PBMCs).
Camila Bastos Ribeiro, Jéssica Cristina dos Santos, Jacyelle Medeiros Silva, Pedro Henrique Silva de Godoi, Marta Regina Magalhães, Mônica Spadafora-Ferreira, Simone Gonçalves Fonseca, Irmtraut Araci Hoffman Pfrimer, A. El-Shazly, U. Musabak, T. Oshima, T. Pessi   +11 more
wiley   +1 more source

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Effect of Chlorogenic Acid (5‐Caffeoylquinic Acid) Isolated from Baccharis oxyodonta on the Structure and Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus terrificus

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The aim of this paper was to investigate the effect of chlorogenic acid (5‐caffeoylquinic acid, 5CQA), isolated from Baccharis oxyodonta, on the structure and pharmacological effect of secretory phospholipase A2 (sPLA2) from Crotalus durissus terrificus.
Daniela O. Toyama, Marcelo J. P. Ferreira, Paulete Romoff, Oriana A. Fávero, Henrique H. Gaeta, Marcos H. Toyama, Sung-Hoon Kim   +6 more
wiley   +1 more source

Hyperactivity, decreased startle reactivity, and disrupted prepulse inhibition following disinhibition of the rat ventral hippocampus by the GABAA receptor antagonist picrotoxin [PDF]

, 2018
.: Rationale: Functional imaging studies have revealed overactivity of the hippocampus in schizophrenic patients. Neuropathological data indicate that hyperactivity of excitatory hippocampal afferents and decreased hippocampal GABA transmission ...
Bast, Tobias, Feldon, Joram, Zhang, Wei-Ning   +2 more
core  

Genetic suppression of transgenic APP rescues hypersynchronous network activity in a mouse model of alzeimer\u27s disease [PDF]

, 2014
Alzheimer's disease (AD) is associated with an elevated risk for seizures that may be fundamentally connected to cognitive dysfunction. Supporting this link, many mouse models for AD exhibit abnormal electroencephalogram (EEG) activity in addition to the
Born, Heather A, Cirrito, John R, Dabaghian, Yuri A, Das, Pritam, Golde, Todd E, Guo, Qinxi, Jankowsky, Joanna L, Kim, Ji-Yoen, Noebels, Jeffrey L, Savjani, Ricky R, Schuler, Dorothy R, Yoo, Jong W, Zheng, Hui   +12 more
core   +2 more sources

Anti-inflammatory peptides and proteins from venomous snakes: a short review

Journal of Biological Research
Inflammation can be acute or chronic. Chronic inflammation is a condition associated with several diseases like cardiovascular and neurodegenerative disorders, and even cancer.
Fernando Lazcano-Pérez, Adrián Marcelo Franco-Vásquez, Ayetza Mathob Rodríguez-García, Roberto Arreguin-Espinosa   +3 more
doaj   +1 more source

Are ticks venomous animals? [PDF]

, 2017
[Introduction]: As an ecological adaptation venoms have evolved independently in several species of Metazoa. As haematophagous arthropods ticks are mainly considered as ectoparasites due to directly feeding on the skin of animal hosts. Ticks are of major
Cabezas-Cruz, Alejandro, Valdés, James J.   +1 more
core   +1 more source

Unlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad [PDF]

, 2023
Funding Information: This work received financial support from PT national funds ( FCT/MCTES , Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the project CIRCNA/BRB/0281/2019 .
Aguiar, Luísa, Almeida, José Rafael, Brioschi, Mariana Borges Costa, Cortes, Sofia, Duarte, Denise, Ferreira, Mariana, Gameiro, Paula, Gomes, Ana S. M., Gomes, Paula, Mendes, Bruno, Miguel, Danilo C., Nogueira, Fátima, Salazar-Valenzuela, David, Teixeira, Cátia A. S.   +13 more
core   +1 more source