Results 11 to 20 of about 10,390 (133)

Redefining CRP in tissue injury and repair: more than an acute pro-inflammatory mediator [PDF]

Frontiers in Immunology
Most early studies investigating the role of C-reactive protein (CRP) in tissue damage determined it supported pro-hemostatic and pro-inflammatory activities.
Marc Potempa, Peter C. Hart, Ibraheem M. Rajab, Lawrence A. Potempa, Lawrence A. Potempa   +4 more
doaj   +2 more sources

C-reactive protein: the nexus between inflammation and protein misfolding diseases [PDF]

Frontiers in Immunology
C-reactive protein (CRP), an acute-phase protein primarily produced by hepatocytes in response to pro-inflammatory cytokines, is a widely used clinical marker for inflammation and tissue damage. In its native state, CRP exists in a stable pentameric form
Abhishek Roy, Abhishek Roy, Johannes Zeller, Johannes Zeller, Tracy L. Nero, Tracy L. Nero, Tracy L. Nero, Johanna Klepetko, Steffen U. Eisenhardt, Michael W. Parker, Michael W. Parker, Michael W. Parker, James D. McFadyen, James D. McFadyen, James D. McFadyen, James D. McFadyen, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter   +19 more
doaj   +2 more sources

How C-Reactive Protein Structural Isoforms With Distinctive Bioactivities Affect Disease Progression

Frontiers in Immunology, 2020
C-reactive protein (CRP) is a widely known, hepatically synthesized protein whose blood levels change rapidly and pronouncedly in response to any tissue damaging event associated with an inflammatory response.
Peter Hart, Ibraheem Rajab, Potempa Lawrence A   +2 more
exaly   +3 more sources

Adiponectin and phase angle in the assessment of sarcopenia in Crohn’s disease: beyond muscle mass [PDF]

Frontiers in Nutrition
IntroductionSarcopenia is a common and clinically relevant complication of Crohn’s disease (CD), reflecting the cross-link among chronic inflammation, malnutrition, and metabolic dysregulation. Adiponectin, an anti-inflammatory adipokine, and phase angle,
Ersilia Nigro, Ersilia Nigro, Maurizio Marra, Francesca De Santis, Francesca De Santis, Rosa Sammarco, Camilla Leo, Olga Maria Nardone, Giulio Calabrese, Alessia Dalila Guarino, Fabiana Castiglione, Aurora Daniele, Aurora Daniele, Fabrizio Pasanisi   +13 more
doaj   +2 more sources

C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit

Reviews in Cardiovascular Medicine, 2023
C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
doaj   +1 more source

Efficient recombinant production of mouse-derived cryptdin family peptides by a novel facilitation strategy for inclusion body formation

Microbial Cell Factories, 2023
Background A number of antimicrobial peptides (AMPs) hold promise as new drugs owing to their potent bactericidal activity and because they are often refractory to the development of drug resistance.
Yuchi Song, Yi Wang, Shaonan Yan, Kiminori Nakamura, Takashi Kikukawa, Tokiyoshi Ayabe, Tomoyasu Aizawa   +6 more
doaj   +1 more source

In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]

PLoS ONE, 2018
The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
doaj   +1 more source

C-reactive protein, immunothrombosis and venous thromboembolism

Frontiers in Immunology, 2022
C-reactive protein (CRP) is a member of the highly conserved pentraxin superfamily of proteins and is often used in clinical practice as a marker of infection and inflammation.
Caroline Dix, Caroline Dix, Johannes Zeller, Johannes Zeller, Hannah Stevens, Hannah Stevens, Hannah Stevens, Steffen U. Eisenhardt, Karen S. Cheung Tung Shing, Karen S. Cheung Tung Shing, Tracy L. Nero, Tracy L. Nero, Craig J. Morton, Craig J. Morton, Craig J. Morton, Michael W. Parker, Michael W. Parker, Michael W. Parker, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter, James D. McFadyen, James D. McFadyen, James D. McFadyen, James D. McFadyen   +24 more
doaj   +1 more source

C-reactive protein in major depressive disorder: Promise and challenge

Journal of Affective Disorders Reports, 2022
Depressive disorders are characterized by persistent low mood, loss of interest and pleasure, decreased energy, varying levels of social and occupational dysfunction.
Angelos Halaris, Danika Prochaska, Ashley Stefanski, Maria Filip   +3 more
doaj   +1 more source

The Multiple Faces of C-Reactive Protein—Physiological and Pathophysiological Implications in Cardiovascular Disease

Molecules, 2019
C-reactive protein (CRP) is an intriguing protein which plays a variety of roles in either physiological or pathophysiological states. For years it has been regarded merely as a useful biomarker of infection, tissue injury and inflammation, and it was ...
Magdalena Boncler, Yi Wu, Cezary Watala
doaj   +1 more source