Results 81 to 90 of about 9,582 (257)

Efficient generation of recombinant RNA viruses using targeted recombination-mediated mutagenesis of bacterial artificial chromosomes containing full-length cDNA [PDF]

, 2013
BACKGROUND: Infectious cDNA clones are a prerequisite for directed genetic manipulation of RNA viruses. Here, a strategy to facilitate manipulation and rescue of classical swine fever viruses (CSFVs) from full-length cDNAs present within bacterial ...
Beer, Martin, Belsham, Graham, Fahnøe, Ulrik, Friis, Martin Barfred, Höper, Dirk, Rasmussen, Thomas Bruun, Reimann, Ilona, Risager, Peter Christian   +7 more
core   +3 more sources

Assessment of the Phenotype and Functionality of Porcine CD8 T Cell Responses following Vaccination with Live Attenuated Classical Swine Fever Virus (CSFV) and Virulent CSFV Challenge [PDF]

Clinical and Vaccine Immunology, 2013
ABSTRACTVaccination with live attenuated classical swine fever virus (CSFV) induces solid protection after only 5 days, which has been associated with virus-specific T cell gamma interferon (IFN-γ) responses. In this study, we employed flow cytometry to characterize T cell responses following vaccination and subsequent challenge infections with ...
Franzoni, G, Kurkure, NV, Edgar, DS, Everett, HE, Gerner, W, Bodman-Smith, KB, Crooke, HR, Graham, SP   +7 more
openaire   +3 more sources

Pathogenicity and Genetic Characterization of Vietnamese Classical Swine Fever Virus: 2014–2018

Pathogens, 2020
Here, we examined the pathogenicity and genetic differences between classical swine fever viruses (CSFV) isolated on pig farms in North Vietnam from 2014−2018. Twenty CSFV strains from 16 pig farms were classified as genotype 2 (sub-genotypes 2.1b,
SeEun Choe, Van Phan Le, Jihye Shin, Jae-Hoon Kim, Ki-Sun Kim, Sok Song, Ra Mi Cha, Gyu-Nam Park, Thi Lan Nguyen, Bang-Hun Hyun, Bong-Kyun Park, Dong-Jun An   +11 more
doaj   +1 more source

RNA self-cleavage activated by ultraviolet light-induced oxidation [PDF]

, 2012
A novel UV-C-light-induced ribozyme activity was discovered within the highly structured 5′-genomic regions of both Hepatitis C Virus (HCV) and the related Classic Swine Fever Virus (CSFV).
Ariza-Mateos, Ascensión, Berzal-Herranz, Alfredo, Birk, A., Díaz-Toledano, Rosa, Gómez, J., Mena Piñeiro, Ignacio, Prieto-Vega, S., Szeto, H.   +7 more
core   +2 more sources

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source

The impact of CSFV on the immune response to control infection [PDF]

Virus Research, 2014
The severity of the acute form of CSF is responsible for the high mortality rate and has been the subject of many studies. Nevertheless, some animals are likely to develop a mild, chronic, or unapparent form of the disease. Paradoxically, this clinical form of the disease has not been well studied, especially regarding its pathogenesis.
Tarradas, Joan, De la Torre Martínez, Ma. Eugènia, Rosell, Rosa, Perez, Lester Josue, Pujols, Joan, Muñoz, Marta, Muñoz, Iván, Muñoz, Sara, Abad, Xavier, Domingo, Mariano, Fraile Sauce, Lorenzo José, Ganges, Llilianne   +11 more
openaire   +3 more sources

Early and Solid Protection Afforded by the Thiverval Vaccine Provides Novel Vaccination Alternatives Against Classical Swine Fever Virus

Vaccines, 2021
Classical swine fever virus (CSFV) remains a challenge for the porcine industry. Inefficient vaccination programs in some endemic areas may have contributed to the emergence of low and moderate virulence CSFV variants.
Yaneysis Lamothe-Reyes, José Alejandro Bohórquez, Miaomiao Wang, Mònica Alberch, Marta Pérez-Simó, Rosa Rosell, Llilianne Ganges   +6 more
doaj   +1 more source

Complete Genome Sequence of Classical Swine Fever Virus Genotype 2.2 Strain Bergen [PDF]

, 2014
The complete genome sequence of the genotype 2.2 classical swine fever virus strain Bergen has been determined; this strain was originally isolated from persistently infected domestic pigs in the Netherlands and is characterized to be of low ...
Floegel-Niesmann, Li, Lohse, Paton, Postel, Rasmussen, Van Oirschot   +6 more
core   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source

African swine fever virus infection in Classical swine fever subclinically infected wild boars

BMC Veterinary Research, 2017
Background Recently moderate-virulence classical swine fever virus (CSFV) strains have been proven capable of generating postnatal persistent infection (PI), defined by the maintenance of viremia and the inability to generate CSFV-specific immune ...
Oscar Cabezón, Sara Muñoz-González, Andreu Colom-Cadena, Marta Pérez-Simó, Rosa Rosell, Santiago Lavín, Ignasi Marco, Lorenzo Fraile, Paloma Martínez de la Riva, Fernando Rodríguez, Javier Domínguez, Llilianne Ganges   +11 more
doaj   +1 more source