Results 91 to 100 of about 714,192 (184)

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen   +12 more
wiley   +1 more source

A scalable workflow for sensitive detection and genomic profiling of tumour cells in lymph nodes from FFPE tissue

open access: yesThe Journal of Pathology, EarlyView.
Abstract Accurate detection of lymph node (LN) metastases is critical for prognosis and surgical decision‐making in head and neck squamous cell carcinoma (HNSCC) and other epithelial cancers. Standard histopathology examines only a small fraction of LN tissue, limiting sensitivity for micrometastases and isolated tumour cells.
Tristan Bergmann   +12 more
wiley   +1 more source

Evolutionary trade‐offs between beauvericin production and growth define divergent virulence strategies in Beauveria

open access: yesPest Management Science, EarlyView.
Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu   +3 more
wiley   +1 more source

Additional file 1 of Post-therapeutic circulating tumor cell-associated white blood cell clusters predict poor survival in patients with advanced driver gene-negative non-small cell lung cancer

open access: yes, 2023
Supplemental Table 1: Correlation analysis between CTCs/CTC-WBC clusters and the clinical characteristics of advanced NSCLC ...
Yanxia Liu (276659)   +9 more
core   +1 more source

Research Progress on Thermal Runaway and Thermal Management of Lithium‐Ion Batteries

open access: yesSafety Science and Technology, EarlyView.
This review summarizes thermal runaway mechanisms, propagation pathways, mitigation strategies, and intelligent thermal management technologies for lithium‐ion batteries, highlighting the transition from passive heat dissipation to integrated safety regulation through advanced cooling, barrier materials, sensing, machine learning, and digital‐twin ...
Songrong Li   +4 more
wiley   +1 more source

Osteological, Biological, and Genetic Consequences of Colonization of Fresh Waters by Marine Cottoid Fishes (Cottidae)

open access: yesIntegrative Zoology, EarlyView.
Lacustrine forms of Triglopsis from North American and European lakes are at different stages of evolution, making them a suitable model for testing hypotheses about evolutionary patterns and rates. An integrative analysis of morphological, genetic, and biological adaptations occurring in lacustrine forms of the genus Triglopsis was carried out.
Valentina G. Sideleva   +4 more
wiley   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

open access: yesAndrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz   +12 more
wiley   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

open access: yesBritish Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher   +6 more
wiley   +1 more source

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)

open access: yes, 2019
Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process.
Marianne Oulhen   +11 more
core   +1 more source

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer

open access: yesBreast Cancer Research, 2018
Background The presence of circulating tumor cells (CTCs) in patients with breast cancer correlates to a bad prognosis. Yet, CTCs are detectable in only a minority of patients with progressive breast cancer, and factors that influence the abundance of ...
Marcus Vetter   +15 more
doaj   +1 more source

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