Results 101 to 110 of about 23,786 (199)

Inverse association between obesity and intestinal endometriosis: Findings from a cross‐sectional study

International Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 1044-1049, August 2026.
Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa, Marco Aurelio Pinho Oliveira   +1 more
wiley   +1 more source

Vaccination Drives Alveolar Macrophages Pool Remodeling via Training Resident Cells and Recruiting Monocyte‐Derived Cells to Defend Against Multidrug‐Resistant Acinetobacter baumannii

MedComm, Volume 7, Issue 8, August 2026.
Under homeostatic conditions, the lungs primarily harbor tissue‐resident alveolar macrophages (TR‐AMs). Intranasal immunization with A. baumannii IWC remodels the alveolar macrophage pool via two complementary mechanisms: recruitment and progressive differentiation of CD11B+CD13+ monocyte‐derived AMs, together with direct functional and epigenetic ...
Xiaomin Zhang, Yangyang Zhou, Chuanying Xiang, Ning Wang, Yan Li, Kai Chen, Yu Xie, Hong Yang, Xiangcheng Sun, Yun Shi   +9 more
wiley   +1 more source

CTCF binding landscape in jawless fish with reference to Hox cluster evolution

Scientific Reports, 2017
The nuclear protein CCCTC-binding factor (CTCF) contributes as an insulator to chromatin organization in animal genomes. Currently, our knowledge of its binding property is confined mainly to mammals.
Mitsutaka Kadota, Yuichiro Hara, Kaori Tanaka, Wataru Takagi, Chiharu Tanegashima, Osamu Nishimura, Shigehiro Kuraku   +6 more
doaj   +1 more source

Harnessing Tumor‐Specific Transcript Diversity Uncovers a Shared Neoantigen Reservoir for Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 8, August 2026.
This study introduces NeoAPP, a computational tool revealing that transcriptional dysregulation generates a dominant reservoir of neoantigens from tumor‐specific transcripts (TSTs) in pancreatic ductal adenocarcinoma (PDAC), far exceeding those of mutational origin.
Jingjing Zhao, Qiaojuan Li, Peng Lin, Yu Yang, Hongwu Yu, Yifan Wen, Wenqian Yu, Huiyi He, Sichen Tao, Feifei Zhang, Yan Li, Zhixiang Hu, Jing Xie, Zhen Chen, Shenglin Huang   +14 more
wiley   +1 more source

Investigator‐Led Research to Improve the Diagnostic Assessment of Platelet Function Disorders: Reflections on the Challenges and Rewards

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 721-731, August 2026.
ABSTRACT Introduction Investigator‐led research and quality improvement initiatives have led to important improvements in the diagnostic assessment of platelet function disorders (PFD). Methods Personal reflections were used to summarize our contributions to knowledge on PFD diagnostic assessment, pathogenesis, and bleeding risks.
Catherine P. M. Hayward
wiley   +1 more source

Telomere Length at Recruitment Predicts Lifespan and Lifetime Reproductive Success in the Barn Swallow (Hirundo rustica)

Molecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT Identifying molecular mechanisms linked to variation in lifespan, reproductive output and sexually selected traits is key to understanding life‐history evolution in wild populations. Telomere length (TL) and attrition (ΔTL) have been proposed as biomarkers of somatic state and maintenance (survival).
Andrea Novelli, Manuela Caprioli, Roberto Ambrosini, Alessandra Costanzo, Diego Rubolini, Marco Parolini, Andrea Romano   +6 more
wiley   +1 more source

CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis

Genome Biology
Background CTCF is considered as the most essential transcription factor regulating chromatin architecture and gene expression. However, genome-wide impact of CTCF on erythropoiesis has not been extensively investigated.
Xue Yang, Li Cheng, Ye Xin, Jianxiang Zhang, Xinfeng Chen, Jinchao Xu, Mengli Zhang, Ruopeng Feng, Judith Hyle, Wenjie Qi, Wojciech Rosikiewicz, Beisi Xu, Chunliang Li, Peng Xu   +13 more
doaj   +1 more source

Context-dependent regulation of IgH V(D)J recombination by cohesin-STAG1 and cohesin-STAG2. [PDF]

Nat Commun
Chang F, Berke-Reynolds B, Yu X, Bush EL, Colón-Rosado JA, Sun L, Wang J, Zhang Y.   +7 more
europepmc   +1 more source

CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression. [PDF]

Proc Natl Acad Sci U S A
Samaniego-Castruita D, Han I, Morgan RC, Carpenter S, Williams B, Chakraborty A, Radhakrishnan I, Ay F, Myers SA, Rao A, Shukla V.   +10 more
europepmc   +1 more source

RNAPII and DNA supercoiling regulate cohesin engagement in neurons. [PDF]

Nucleic Acids Res
Crewe M, Delint-Ramirez I, Halawa O, Heady L, Madabhushi R.   +4 more
europepmc   +1 more source