Results 121 to 130 of about 120,218 (287)

Figure S4 from Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4⁺Foxp3⁻ Cell–Mediated Modulation of CD103⁺ Dendritic Cells [PDF]

, 2023
Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Alexander J. Davenport, Emma V. Petley, Imran G. House, Junyun Lai, Kevin Sek, Nicole Milenkovski, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Joseph A. Trapani, Sherene Loi, Michael H. Kershaw, Nicole M. Haynes, Phillip K. Darcy   +16 more
openalex   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Supplementary Table S7 from A Phase II Window of Opportunity Study of Neoadjuvant PD-L1 versus PD-L1 plus CTLA-4 Blockade for Patients with Malignant Pleural Mesothelioma

, 2023
Hyun‐Sung Lee, Hee-Jin Jang, Maheshwari Ramineni, Daniel Wang, Daniela Ramos, Jong Min Choi, Taylor Splawn, Monica Espinoza, Michelle Almarez, Leandria Hosey, Eunji Jo, Susan G. Hilsenbeck, Christopher I. Amos, R. Taylor Ripley, Bryan M. Burt   +14 more
openalex   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

, 2013
Margaret K. Callahan, Jedd D. Wolchok
openalex   +1 more source

Data from CD4 T Cells Require ICOS-Mediated PI3K Signaling to Increase T-Bet Expression in the Setting of Anti-CTLA-4 Therapy

, 2023
Hong Chen, Tihui Fu, Woong‐Kyung Suh, Dimitra Tsavachidou, Sijin Wen, Jianjun Gao, Derek Ng Tang, Qiuming He, Jingjing Sun, Padmanee Sharma   +9 more
openalex   +1 more source

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

Single-nucleotide polymorphism of CTLA-4 (rs5742909) in correlation with schizophrenia risk factor

, 2019
MelisaI Barliana, Riyadi Sumirtanurdin, JamesP Laksono, Haafizah Dania, FitriN Ramadhani, DyahA Perwitasari, Rizky Abdulah   +6 more
openalex   +1 more source

Figures S1 and S2 from VEGF Neutralization Plus CTLA-4 Blockade Alters Soluble and Cellular Factors Associated with Enhancing Lymphocyte Infiltration and Humoral Recognition in Melanoma

, 2023
Xinqi Wu, Anita Giobbie‐Hurder, Xiaoyun Liao, Donald P. Lawrence, David F. McDermott, Jun Zhou, Scott J. Rodig, F. Stephen Hodi   +7 more
openalex   +1 more source