Immature dendritic cells induce hyporesponsiveness to alloantigens in vitro and prolong mouse cardiac allograft survival [PDF]
Fu, F +5 more
core
Sleep Deprivation Alters T Cell Dynamics: Melatonin as a Restorative Agent
ABSTRACT Sleep is an essential physiological function regulated by circadian rhythm and homeostatic regulation for emotional and physical health. Conversely, sleep deprivation (SD) is associated with weakened immune system function and overall health, which potentially leads to chronic diseases such as heart disease and diabetes.
Hilal Öztürk +8 more
wiley +1 more source
A novel <i>CTLA-4</i> deletion variant in a child with refractory autoimmune hemolytic anemia: molecular and functional characterization. [PDF]
Chen F +6 more
europepmc +1 more source
Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study
ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen +3 more
wiley +1 more source
Soluble CTLA-4 and high-risk genetic variants: A new frontier in pancreatic ductal adenocarcinoma (PDAC) biomarkers. [PDF]
Hassan M +4 more
europepmc +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
Depletion of CD25<sup>+</sup> cells restores Th1, Th2 and Th17 responses and mitigates Eimeria maxima infection in chickens. [PDF]
Pan Y +8 more
europepmc +1 more source
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Converting 'cold' to 'hot' hepatocellular carcinoma for improved immunotherapy (Review)
Hsieh CH, Chuang PC.
europepmc +1 more source
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie +9 more
wiley +1 more source

