Results 61 to 70 of about 8,409 (203)

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Cuproptosis-related genes.

The Cuproptosis-related genes used in the manuscript. (DOCX)
Xiaochen Pei (18389120), Jia Song (495396), Lin Wang (11986), Jia Li (160557), Jiajun Chen (1279269)   +4 more
core   +1 more source

DataSheet2_Revealing prognostic and tumor microenvironment characteristics of cuproptosis in bladder cancer by genomic analysis.XLSX

, 2022
Objectives: Bladder cancer (BLCA) is the most common malignant tumor in the urinary system, while the prognosis of muscle-invasive bladder cancer (MIBC) is poor. Cuproptosis might be a promising therapeutic approach to trigger tumor cell death.
Haibo Shen (4412893), Shun Zhang (334141), Chen Wang (88408), Weimin Xia (11750027), Huangqi Duan (7440791), Shenggen Yu (13895607)   +5 more
core   +1 more source

Cuproptosis as a novel predictor of immunotherapy response and shapes the immune landscape in pan-cancer analysis

Discover Oncology
The heterogeneity of cancer renders its response to immunotherapy elusive, warranting the identification of robust biomarkers for evaluation. As a form of recently defined regulated cell death (RCD), cuproptosis is driven by copper-dependent proteotoxic ...
Yitong Pan, Xiaodi Hu, Jun Cheng
doaj   +1 more source

Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues

Journal of Orthopaedic Translation
Background: Cuproptosis, a newly identified form of cell death, presents an as-yet-unclear potential correlation with Osteoarthritis (OA) pathogenesis. This study aimed to explore the relationship between chondrocyte cuproptosis and OA, and to evaluate ...
Haotian Hua, Feng Cheng, Zhuo Meng, Anqi Zhang, Mengying Li, Minjie Zhang, Pengqiang Lou, Yiwen Zhu, Peijian Tong, Yang Zhang   +9 more
doaj   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

The molecular mechanisms of cuproptosis and its relevance to atherosclerosis [PDF]

Atherosclerosis is a chronic inflammatory disease associated with lipid deposition in the vascular intima. Copper is a vital trace element implicated in the onset and progression of atherosclerosis.
Hang Shang, Chen, Zhian, Jiankang Wang, Wang, Jiankang, Zhian Chen, Jiajuan Guo, Guo, Jiajuan, Shang, Hang   +7 more
core   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Table1_Revealing prognostic and tumor microenvironment characteristics of cuproptosis in bladder cancer by genomic analysis.DOCX

, 2022
Objectives: Bladder cancer (BLCA) is the most common malignant tumor in the urinary system, while the prognosis of muscle-invasive bladder cancer (MIBC) is poor. Cuproptosis might be a promising therapeutic approach to trigger tumor cell death.
Haibo Shen (4412893), Shun Zhang (334141), Chen Wang (88408), Weimin Xia (11750027), Huangqi Duan (7440791), Shenggen Yu (13895607)   +5 more
core   +1 more source