Results 161 to 170 of about 19,999 (211)

The role of chemokines and their receptors in cardiovascular diseases. [PDF]

open access: yesFront Immunol
Srikanth S   +3 more
europepmc   +1 more source

CXC chemokines in angiogenesis [PDF]

open access: yesCytokine and Growth Factor Reviews, 2005
CXC chemokines display pleiotropic effects in immunity, regulating angiogenesis, and mediating organ-specific metastases of cancer. In the context of angiogenesis, CXC chemokines are a unique family of cytokines, known for their ability to behave in a disparate manner in the regulation of angiogenesis.
Robert M Strieter   +2 more
exaly   +4 more sources

Phylogenetic analysis of vertebrate CXC chemokines reveals novel lineage specific groups in teleost fish [PDF]

open access: yesDevelopmental and Comparative Immunology, 2013
In this study, we have identified 421 molecules across the vertebrate spectrum and propose a unified nomenclature for CXC chemokines in fish, amphibians and reptiles based on phylogenetic analysis.
Qiaoqing Xu   +2 more
exaly   +2 more sources
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CXC chemokines in angiogenesis of cancer

Seminars in Cancer Biology, 2004
The CXC chemokine family are unique cytokines known for their ability to have dual functions in the regulation of angiogenesis related to the following: (1) the presence or absence of the structural/functional motif (Glutamic acid-Leucine-Arginine; 'ELR' motif) that immediately precedes the first cysteine amino acid residue in the primary structure of ...
Robert M Strieter   +2 more
exaly   +3 more sources

Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites [PDF]

open access: yesFEBS Journal, 2004
Three novel CXC chemokines were identified in common carp (Cyprinus carpio L.) through homology cloning. Phylogenetic analyses show that one of the three CXC chemokines is an unambiguous orthologue of CXCL14, whereas both others are orthologues of CXCL12,
Mark O Huising   +2 more
exaly   +2 more sources

ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets

Pharmacology & Therapeutics, 2006
ELR+ CXC chemokines, by direct interaction with their cell surface receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2), are believed to be crucially involved in the direct migration and activation of leukocytes. ELR+ CXC chemokines are supposed to play a key role in several inflammatory diseases and this makes ELR+ CXC ...
Cinzia Bizzarri   +2 more
exaly   +3 more sources

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