Results 171 to 180 of about 1,829 (202)
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CXCR4-CXCL12-Dependent Inflammatory Network and Endothelial Progenitors
Current Medicinal Chemistry, 2010The endothelial progenitor cells (EPCs) are angiogenic cells having properties similar to those of embryonal angioblasts. The number and function of EPCs are affected by a variety of conditions, including cytokines and chemokines, which are pivotal inflammatory signaling molecules. The purpose of this paper is to review current knowledge about the role
SALVATORE, PAOLA +3 more
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ความสำคัญและที่มาปัญหาการวิจัย : 14-40% ผู้ป่วยมะเร็งปอดชนิดไม่เล็กระยะลุกลามจะเกิดมะเร็งกระจายไปที่กระดูกและประมาณครึ่งหนึ่งจะเกิดภาวะแทรกซ้อนตามมา (1) ซึ่งมีผลต่อคุณภาพชีวิตและอัตราการรอดชีวิตที่ 2 ปี เท่ากับ 11.3%(2) ถึงแม้ว่าการทำ Bone scan และ FDG-PET จะมีความไวและความจำเพาะที่สูง แต่ก็ยังพบว่ามีผลลบและผลบวกลวงได้ในชนิดมะเร็งที่มีการกัดกร่อนท ...
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Glioblastomas: Role of CXCL12 Chemokine
2010Chemokines are small pro-inflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane receptors on the plasma membrane of target cells. They are also the major regulators of cell trafficking. Chemokines and their receptors were initially associated with the trafficking of leukocytes during physiological immune
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CXCR4/CXCL12 as a Therapeutic Target
2014The interaction of acute myeloid leukemia (AML) blasts with the bone marrow microenvironment regulates critical processes important in sustaining the malignant clone including self-renewal, cell growth, and proliferation as well as resistance to chemotherapy.
Geoffrey L. Uy, John F. DiPersio
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Heparin and CXCL12 Dimerization
Journal of Clinical Oncology, 2005Kadri Altundag +2 more
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CXCL12/CXCR4: An amazing challenge and opportunity in the fight against fibrosis
Ageing Research Reviews, 2023Yang Yang
exaly
The unique structural and functional features of CXCL12
Cellular and Molecular Immunology, 2017Rik Janssens, Sofie Struyf, Paul Proost
exaly

