ARAP1 fine-tunes F-actin polymerization level in lymphocytes through RhoA inhibition. [PDF]
Ueda Y, Kondo N, Kamioka Y, Kinashi T.
europepmc +1 more source
CXCL12 (SDF-1α) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells [PDF]
Moran Meiron +4 more
openalex +1 more source
CXCL12 expression predicts survival in Radically Resected (R0) primary pancreatic adenocarcinoma
Crescenzo D’Alterio +14 more
openalex +1 more source
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi +2 more
wiley +1 more source
Study on the regulation of Treg cell infiltration by EZH2 through CXCR4/CXCL12 in diffuse large B-cell lymphoma. [PDF]
Wang H +5 more
europepmc +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
Plasma Level of Stromal Cell-Derived Factor-1 Provides Insight Into Statin Response, But Not Into Left Ventricular Dysfunction in New Unstable Angina. [PDF]
Murad H, Qutub M.
europepmc +1 more source
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos +4 more
wiley +1 more source
Single cell transcriptomic profiling uncovers shared inflammatory pathways and immune dysregulation underlying the asthma to lung cancer transition. [PDF]
Huang H +6 more
europepmc +1 more source

